79083-42-4Relevant articles and documents
Unexpected furanose/pyranose equilibration of N-glycosyl sulfonamides, sulfamides and sulfamates
Suthagar, Kajitha,Polson, Matthew I. J.,Fairbanks, Antony J.
, p. 6573 - 6579 (2015)
De-protected arabino N-glycosyl sulfamides, sulfonamides and sulfamates were found to mutarotate and convert from the furanose to the thermodynamically more stable pyranose form in aqueous solution. The presence of a strongly electron withdrawing group in
Asymmetric Formal Synthesis of (-)-Swainsonine from Chiral-Pool Precursors d -Mannose and d -Arabinose
Chuanopparat, Nutthawat,Kongkathip, Boonsong,Kongkathip, Ngampong,Lamor, Anphisa,Ngernmeesri, Paiboon,Uipanit, Suwanan,Yakhampom, Sujitra
, (2022/02/23)
Carbohydrates have played an important role in organic synthesis. Since they contain many stereocenters, they have been widely used as chiral-pool starting materials. Herein, we report the asymmetric formal synthesis of (-)-swainsonine, which exhibits anticancer and immunosuppressive activities and inhibits lysosomal α-mannosidase activity, from D-mannose and D-arabinose. The synthesis utilized Zn-mediated Bernet-Vasella reaction, Horner-Wadsworth-Emmons olefination, and Grubbs olefin metathesis as key reactions.
Preparation method of compound with 3, 4-trans-3, 6-anhydrofuran hexose structure
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Paragraph 0020, (2021/05/15)
The invention discloses a preparation method of a compound with a 3, 4-trans-3, 6-dehydrated furan hexose structure and a preparation method of the compound with the 3, 4-trans-3, 6-dehydrated furan hexose structure. The method comprises the following ste
Novel saccharide bio-based cyclic phosphorus/phosphonate as well as preparation method and application thereof
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Paragraph 0039; 0041-0042, (2021/09/04)
The invention discloses novel saccharide bio-based cyclic phosphorus/phosphonate as well as a preparation method and application thereof, and belongs to the field of compounds. The cyclic phosphorus/phosphonate is prepared by the following steps: reacting D-xylose with acetyl chloride to obtain an intermediate product, and then reacting with dichlorophosphate or phosphonic dichloride under the action of an acid-binding agent to obtain a target product. The preparation method is high in yield, simple in process, low in raw material cost and small in environmental pollution, and the prepared cyclic phosphorus/phosphonate flame retardant is outstanding in flame retardance and easy to industrialize.