4894-23-9

Basic information

• Product Name: 3,5-Diphenyl-2-isoxazoline
• Synonyms: 3,5-Diphenyl-2-isoxazoline;3,5-diphenyl-4,5-dihydro-1,2-oxazole
• CAS NO: 4894-23-9
• Molecular Formula: C₁₅H₁₃NO
• Molecular Weight: 223.2698
• Mol File: 4894-23-9.mol
• Article Data: 67

Chemical Properties

• Boiling Point: 351.4°Cat760mmHg
• Flash Point: 135.4°C
• Appearance: /
• Density: 1.11g/cm³
• Vapor Pressure: 8.37E-05mmHg at 25°C
• Refractive Index: 1.601
• CAS DataBase Reference: 3,5-Diphenyl-2-isoxazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Diphenyl-2-isoxazoline(4894-23-9)
• EPA Substance Registry System: 3,5-Diphenyl-2-isoxazoline(4894-23-9)

Safety Data

• Hazardous Substances Data: 4894-23-9(Hazardous Substances Data)

Usage

General Description

3,5-Diphenyl-2-isoxazoline is a chemical compound with the molecular formula C15H11NO. It is an isoxazoline derivative, which is a type of heterocyclic compound containing a five-membered ring with oxygen and nitrogen atoms. 3,5-Diphenyl-2-isoxazoline is used as a building block in the synthesis of various pharmaceuticals and agrochemicals due to its unique structural and chemical properties. It has also been studied for its potential biological activities, including as an antiproliferative agent against cancer cells and as an anti-inflammatory agent. Additionally, 3,5-Diphenyl-2-isoxazoline has applications in material science, specifically in the development of advanced polymers and liquid crystals due to its ability to form stable and complex molecular structures. Overall, this compound has diverse potential applications in the fields of medicine, agriculture, and material science.

InChI:InChI=1/C15H13NO/c1-3-7-12(8-4-1)14-11-15(17-16-14)13-9-5-2-6-10-13/h1-10,15H,11H2

Upstream product

• 156605-56-0 1-phenylethan-1-one O-pivaloyl oxime 
• 100-52-7 benzaldehyde 
• 76951-53-6 E-C-phenyl-C-(E-β-styryl)-N-methylthiomethylnitrone 
• 1138-48-3 cis-1,2-diphenylcyclopropane 
• 100-42-5 styrene 
• 108199-02-6 O-ethoxycarbonylbenzohydroximoyl chloride 
• 20141-73-5 benzaldehyde oxime O-tributylstannyl ether 
• 932-90-1 syn-benzaldehyde oxime 
• 622-42-4 1-nitro-1-phenylmethane 
• 614-47-1 1,3-diphenyl-propen-3-one 
• 698-16-8 benzohydroximoyl chloride 
• 94-41-7 benzalacetophenone 
• 384814-07-7 N,N'-bis-(3-oxo-1,3-diphenyl-propyl)-hydroxylamine 
• 32831-01-9 3-chloro-3-phenylpropiophenone 

Downstream Products

• 13286-60-7 (±)-3-amino-1,3-diphenylpropan-1-ol 
• 13286-60-7 (±)-3-amino-1,3-diphenylpropan-1-ol 
• 614-47-1 1,3-diphenyl-propen-3-one 
• 4888-31-7 3-Acetoxy-3-phenyl-propionsaeure-anilid 
• 4198-15-6 3-hydroxy-N,3-diphenylpropanamide 
• 3056-73-3 N-phenylcinnamamide 
• 80012-16-4 3-amino-1,3-diphenyl-2-propene-1-onate 
• 98815-39-5 (Z)-3-amino-1,3-diphenylprop-2-en-1-one 
• 42052-51-7 3-hydroxy-1,3-diphenylpropan-1-one 
• 18732-48-4 1-acetoxy-2-(5-phenyl-4,5-dihydro-isoxazol-3-yl)-benzene 
• 1106719-40-7 (1S,3R)-3-benzoylamino-1,3-diphenyl-1-propanol 
• 91875-60-4 (1S,3S)-3-benzoylamino-1,3-diphenyl-1-propanol 
• 91875-60-4 (1R,3S)-3-benzoylamino-1,3-diphenyl-1-propanol 
• 211998-03-7 (R)-3,5-diphenyl-2-isoxazoline 

Relevant articles and documents

Gold-Catalyzed Cyclization/Intermolecular Methylene Transfer Sequence of O-Propargylic Oximes Derived from Glyoxylates

We successfully extended our gold-catalyzed skeletal rearrangement reaction of O -propargylic oximes through C=N bond cleavage to include substrates having an ester group on the oxime moiety, affording the corresponding 2-isoxazolines having an alkoxycarb

TEMPO-Mediated Selective Synthesis of Isoxazolines, 5-Hydroxy-2-isoxazolines, and Isoxazoles via Aliphatic δ-C(sp3)-H Bond Oxidation of Oximes

Selective synthesis of three different bioactive heterocycles; isoxazolines, 5-hydroxy-2-isoxazolines and isoxazoles from the same starting material using TEMPO (2,2,6,6-Tetramethylpiperidin-1-oxyl) as a radical initiator is reported. Selectivity was achi

Heteroannulation of Alkenes with Enynyl Benziodoxolones and Silver Nitrite Involving CC bond Oxidative Cleavage: Entry to 3-Aryl-?2-isoxazolines

A copper-catalyzed [2 + 2 + 1] heteroannulation of alkenes with enynyl benziodoxolones and AgNO2 involving oxidative cleavage of the CC bond promoted by cooperative Zn(OTf)2, KOAc, and 4 ? MS for producing 3-aryl δ2-isoxazolines is reported. Mechanistic s