491-39-4

Basic information

• Product Name: 1-thiochromone
• Synonyms: 1-thiochromone;4H-1-Benzothiopyran-4-one
• CAS NO: 491-39-4
• Molecular Formula: C₉H₆OS
• Molecular Weight: 162.21
• Mol File: 491-39-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-thiochromone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-thiochromone(491-39-4)
• EPA Substance Registry System: 1-thiochromone(491-39-4)

Safety Data

• Hazardous Substances Data: 491-39-4(Hazardous Substances Data)

Usage

General Description

1-thiochromone is a heterocyclic organic compound with a sulfur atom in the place of one of the oxygen atoms in chromone. It is a yellow crystalline solid with a molecular formula of C9H6OS and a molecular weight of 162.21 g/mol. 1-thiochromone has a fused ring structure and exhibits both aromatic and ketonic properties. It is commonly used as a building block in organic synthesis and pharmaceutical research due to its unique structure and reactivity. 1-thiochromone has shown potential in the development of new drugs and materials, making it a subject of interest in various fields of chemistry and medicinal science.

InChI:InChI=1/C9H6OS/c10-8-5-6-11-9-4-2-1-3-7(8)9/h1-6H

Upstream product

• 513-48-4 2-butyl iodide 
• 637-89-8 4-sulfanylphenol 
• 55454-08-5 4-(trimethylsilyloxy)thiochrom-3-ene 
• 120-92-3 cyclopentanone 
• 70030-52-3 S-phenyl thiocinnamate 

Downstream Products

• 5962-00-5 2-phenyl-thiochroman-4-one 
• 826-86-8 2-methyl-1-thiochroman-4-one 
• 6928-51-4 2-phenylthiochroman-4-ol 
• 784-62-3 1-thioflavone 
• 5738-23-8 12H-thiochromeno[2,3-b]quinolin-12-one 
• 166045-40-5 2-(4-fluorophenyl)-2,3-dihydro-4H-1-benzothiopyran-4-one 
• 1135136-54-7 2-(4-methoxyphenyl)thiochroman-4-one 

Relevant articles and documents

Benzpyrylium squarylium and croconylium dyes, and processes for their preparation and use

Dyes comprising an inner salt of a compound of the formula: wherein: Q1 is a 4-(benz[b]-4H-pyrylium)methylidene, 4-(benz[b]-4H-thiopyrylium)methylidene or 4-(benz[b]-4H-selenopyrylium)methylidene grouping; Z is a 1,3-(2-hydroxy-4-oxo-2-cyclobutylidene) hydroxide or 1,3-(2-hydroxy-4,5-dioxo-2-cyclopentylidene) hydroxide ring; and Q2 is a 4-(benz[b]-4H-pyran-4-ylidene)methyl, 4-(benz[b]-4H-thiopyran-4-ylidene)methyl or 4-(benz[b]-4H-selenopyran-4-ylidene)methyl grouping; wherein at least one of the groupings Q1 and Q2 carries at its 2-position a substituent in which a non-aromatic carbon atom is bonded directly to the benzpyrylium, benzthiopyrylium or benzselenopyrylium nucleus, subject to the proviso that if this 2-substituent contains an aromatic nucleus, this aromatic nucleus is not conjugated with the benzpyrylium, benzthiopyrylium or benzselenopyrylium nucleus to which it is attached, are useful as visible and near infra-red absorbers, having high extinction coefficients and improved solubility in polymeric media.

A general route to the synthesis of 3-alkylidene derivatives of 4-thiochromanone 1,1-dioxide

The reactions of the trimethylsilyl enol ethers of both 4-thiochromanone and 4-thiochromanone 1,1-dioxide with various carbonyl compounds complexed with titanium tetrachloride give moderate yields of the previously unknown 3-alkylidene condensation products under mild conditions.Other Lewis acids, with the exception of boron trifluoride, were found to be ineffective in this transformation.