4968-87-0

Basic information

• Product Name: piperidin-1-yl(pyridin-4-yl)methanone
• Synonyms: piperidin-1-yl(pyridin-4-yl)methanone
• CAS NO: 4968-87-0
• Molecular Formula: C₁₁H₁₄N₂O
• Molecular Weight: 190.24166
• Mol File: 4968-87-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 345.3±15.0 °C(Predicted)
• Appearance: /
• Density: 1.134±0.06 g/cm3(Predicted)
• PKA: 4.56±0.10(Predicted)
• CAS DataBase Reference: piperidin-1-yl(pyridin-4-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: piperidin-1-yl(pyridin-4-yl)methanone(4968-87-0)
• EPA Substance Registry System: piperidin-1-yl(pyridin-4-yl)methanone(4968-87-0)

Safety Data

• Hazardous Substances Data: 4968-87-0(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 55-22-1 pyridine-4-carboxylic acid 
• 201230-82-2 carbon monoxide 
• 19524-06-2 4-bromopyridine hydrochloride 
• 100-48-1 pyridine-4-carbonitrile 
• 108-89-4 picoline 
• 34490-39-6 4-((piperidin-1-yl)methyl)pyridine 
• 872-85-5 pyridine-4-carbaldehyde 
• 1570-45-2 isonicotinic acid ethylester 
• 29211-88-9 N-Methyl-N-benzyl-isonicotinamid 
• 15854-87-2 4-iodopyridine 

Downstream Products

• 63214-58-4 piperidin-4-yl-piperidin-1-yl-methanone 
• 80030-54-2 N-(2-Cyano-4,5-dimethoxy-phenyl)-4-(piperidine-1-carbonyl)-piperidine-1-carboximidothioic acid methyl ester 
• 86543-11-5 4-(Piperidine-1-carbonyl)-piperidine-1-carbothioic acid (2-cyano-4,5-dimethoxy-phenyl)-amide 
• 278598-12-2 1-(piperidin-4-ylcarbonyl)piperidine hydrochloride 
• 29211-88-9 N-Methyl-N-benzyl-isonicotinamid 
• 88057-93-6 (piperidin-1-yl)(pyridin-4-yl)methanethione 
• 16781-67-2 2-morpholin-4-yl-2-thiazole-4(5H)-one 

Relevant articles and documents

Cobalt-catalyzed aminocarbonylation of (hetero)aryl halides promoted by visible light

The catalytic aminocarbonylation of (hetero)aryl halides is widely applied in the synthesis of amides but relies heavily on the use of precious metal catalysis. Herein, we report an aminocarbonylation of (hetero)aryl halides using a simple cobalt catalyst under visible light irradiation. The reaction extends to the use of (hetero)aryl chlorides and is successful with a broad range of amine nucleophiles. Mechanistic investigations are consistent with a reaction proceeding via intermolecular charge transfer involving a donor-acceptor complex of the substrate and cobaltate catalyst.

Tri-Functional Elemental Sulfur Enabling Bis-Heteroannulation of Methyl Ketoximes with Methyl N-Heteroarenes

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Cross-Dehydrogenating Coupling of Aldehydes with Amines/R-OTBS Ethers by Visible-Light Photoredox Catalysis: Synthesis of Amides, Esters, and Ureas

A straightforward synthesis of amides, ureas, and esters is reported by visible-light cross-dehydrogenating coupling (CDC) of aldehydes (or amine carbaldehydes) and amines/R-OTBS ethers by photoredox catalysis. The reaction is found to be general and high yielding. A plausible mechanistic pathway has been proposed for these transformations and is supported by appropriate controlled experiments.