4986-28-1

Basic information

• Product Name: Phenol, 2-(2-benzofuranyl)-
• CAS NO: 4986-28-1
• Molecular Formula: C14H10O2
• Molecular Weight: 210.232
• Mol File: 4986-28-1.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Phenol, 2-(2-benzofuranyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-(2-benzofuranyl)-(4986-28-1)
• EPA Substance Registry System: Phenol, 2-(2-benzofuranyl)-(4986-28-1)

Safety Data

• Hazardous Substances Data: 4986-28-1(Hazardous Substances Data)

Usage

General Description

Phenol, 2-(2-benzofuranyl)- is a chemical compound with the molecular formula C14H10O2. It is an organic compound belonging to the phenol family, with a benzofuran ring attached to the 2-position of the phenol ring. Phenol, 2-(2-benzofuranyl)- is used as a building block in the synthesis of various pharmaceuticals and organic compounds. It has also been studied for its potential biological activities, including anti-inflammatory and antioxidant properties. Additionally, it is used as a research chemical in the study of organic synthesis and medicinal chemistry. Overall, Phenol, 2-(2-benzofuranyl)- is a versatile compound with potential applications in various fields.

Upstream product

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• 17601-37-5 (E)-2,2'-dimethoxystilbene 
• 18221-50-6 dihydroxy-stilbene 
• 64820-07-1 ((2-methoxyphenyl)methyl)triphenylphosphonium bromide 
• 135-02-4 ortho-anisaldehyde 
• 18221-50-6 2,2’-(1,2-ethenediyl)bis-phenol 
• 533-58-4 2-Iodophenol 
• 1216963-74-4 lithium acetylide-ethylenediamine complex 
• 1170724-22-7 tert-butyl(2-((2-methoxyphenyl)ethynyl)phenoxy)dimethylsilane 
• 937716-60-4 (E)-1-(2-hydroxyphenyl)ethanone O-phenyloxime 
• 67088-23-7 2,2'-Bis-methoxymethoxy-benzoin 

Downstream Products

• 100527-27-3 2-benzofuran-2-yl-4,6-dinitro-phenol 
• 102184-01-0 2-(2-benzoyloxy-phenyl)-benzofuran 

Relevant articles and documents

Aerobic Copper-Catalyzed Intramolecular Cascade Oxidative Isomerization/[4+4] Cyclization of 2,2′-Disubstituted Stilbenes

An aerobic copper-catalyzed cascade oxidative isomerization/[4+4] cyclization of 2,2′-disubstituted stilbenes is described. Under the mild CuCl/DBED/air catalytic system, various 5,10-heteroatom-containing tetrahydroindeno[2,1-a]indenes were efficiently p

Palladium-Catalyzed Domino Process: Synthesis of Symmetrical Diarylalkynes, cis- and trans-Alkenes using Lithium Acetylide as a Synthon

An efficient domino protocol has been developed for the synthesis of symmetrical diarylalkynes. Notably, the method was successful in the presence of a palladium catalyst without the support of a copper co-catalyst. Significantly, the method enabled the use of the commercially available and cheap lithium acetylide ethylenediamine complex as a source of acetylene for the construction of dual C-C bonds, with a wide range of compatibility towards various substituents of the aryl bromides/iodides. Significantly, this protocol was successfully applied to the synthesis of cis- and trans-alkenes in a highly stereoselective manner in a sequential one-pot process.

Copper-catalyzed oxidative aromatization of 2-cyclohexen-1-ones to phenols in the presence of catalytic hydrogen bromide under molecular oxygen

Catalytic oxidative aromatization has been achieved using 2-cyclohexen-1-ones to obtain phenol derivatives in the presence of a catalytic amount of copper salt and aqueous HBr under molecular oxygen. The amount of HBr was successfully reduced to a catalytic quantity, and the other additive such as a ligand and an oxidant as well as inert conditions were unnecessary. Various mono-, di-, and trisubstituted phenols with substituents at the desired positions could be synthesized under cheap and simple conditions. An oxidative aromatization/bromination sequence was also demonstrated to obtain bromophenols with excess HBr. The Royal Society of Chemistry 2013.