7424-57-9

Basic information

• Product Name: Ethanone, 2-hydroxy-1,2-bis(2-hydroxyphenyl)-
• CAS NO: 7424-57-9
• Molecular Formula: C14H12O4
• Molecular Weight: 244.247
• Mol File: 7424-57-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-hydroxy-1,2-bis(2-hydroxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-hydroxy-1,2-bis(2-hydroxyphenyl)-(7424-57-9)
• EPA Substance Registry System: Ethanone, 2-hydroxy-1,2-bis(2-hydroxyphenyl)-(7424-57-9)

Safety Data

• Hazardous Substances Data: 7424-57-9(Hazardous Substances Data)

Upstream product

• 5533-04-0 2-(methoxymethoxy)benzaldehyde 
• 7664-93-9 sulfuric acid 
• 67088-23-7 2,2'-Bis-methoxymethoxy-benzoin 
• 64-19-7 acetic acid 
• 90-02-8 salicylaldehyde 

Downstream Products

• 1233532-04-1 2-(5-(2-hydroxyphenyl)-2-phenyl-1H-imidazol-4-yl)phenol 
• 1364967-56-5 C₂₁H₁₅N₃O₄ 
• 85-26-7 2,2'-dihydroxybenzil 
• 4986-28-1 2-(benzofuran-2-yl)phenol 
• 7622-42-6 2,2'-dihydroxydeoxybenzoin 

Relevant articles and documents

Development of Imidazoline-2-one Derivatives as Potential Antifungal and Anthelminthic Agents: in silico and in vitro Evaluation

Based on appropriate values of synthetic accessibility concerning from ADMET properties and docking scores by docking against proteins 3OZU and 1OJ0, a series of 4,5-diphenyl-1H-imidazol-2-ones (I1?15) were synthesized. The key intermediate, 2-hydroxy-1,2-disubstitutedethanones (E1?15) were prepared by benzoin condensation using 2:1 ratio of aromatic aldehydes and thiamine in the presence of alkali. Further, these cyclized ethanones (E1?15) were treated with urea to yield 4,5-diphenyl-1H-imidazol-2-one derivatives (I1?15) and were characterized by IR,1H NMR, Mass spectra, and CHNO analysis. The synthesized compounds were screened for their anthelmintic potential on Pheretima Posthuma along with standard albendazole, and antifungal activity (minimum inhibitory concentration method) on Candida albicans and Aspergillus niger along with standard miconazole. The results revealed that among all the tested compounds I3, I4, and I7 show considerable synthetic accessibility, docking scores, anthelminthic, and antifungal activity.