500547-59-1

Basic information

• Product Name: [4-(2-methylpropoxy)phenyl]methanol
• Synonyms: [4-(2-methylpropoxy)phenyl]methanol
• CAS NO: 500547-59-1
• Molecular Formula: C11H16O2
• Molecular Weight: 180.24354
• Mol File: 500547-59-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [4-(2-methylpropoxy)phenyl]methanol(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(2-methylpropoxy)phenyl]methanol(500547-59-1)
• EPA Substance Registry System: [4-(2-methylpropoxy)phenyl]methanol(500547-59-1)

Safety Data

• Hazardous Substances Data: 500547-59-1(Hazardous Substances Data)

Usage

Description

[4-(2-methylpropoxy)phenyl]methanol is an organic compound characterized by its chemical formula C11H16O2. It is a white solid that features a phenyl ring with a methoxy group attached to the fourth carbon atom and a methanol group attached to the first carbon atom. [4-(2-methylpropoxy)phenyl]methanol is known for its versatile applications in various industries and research fields.

Uses

Used in Pharmaceutical Industry:
[4-(2-methylpropoxy)phenyl]methanol is used as a building block for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medical treatments.
Used in Agrochemical Industry:
In the agrochemical industry, [4-(2-methylpropoxy)phenyl]methanol is utilized as a starting material for the creation of different agrochemicals. Its properties make it suitable for use in the development of pesticides, herbicides, and other agricultural products that aim to improve crop yield and protect plants from pests.
Used in Material Science:
[4-(2-methylpropoxy)phenyl]methanol has potential applications in the development of new materials. Its chemical structure can be manipulated to create innovative materials with unique properties, which can be applied in various fields such as electronics, automotive, and aerospace industries.
Used as a Reagent in Organic Chemistry:
[4-(2-methylpropoxy)phenyl]methanol also serves as a reagent in organic chemistry reactions. Its versatility and reactivity make it a valuable tool for researchers and chemists in the synthesis of complex organic compounds and the exploration of new chemical reactions.

Upstream product

• 78-77-3 Isobutyl bromide 
• 623-05-2 (4-hydroxyphenyl)methanol 
• 513-38-2 Isobutyl iodide 
• 513-36-0 isobutyryl chloride 
• 1015423-08-1 ethyl 4-(2-methylpropoxy)benzoate 
• 120-47-8 Ethyl 4-hydroxybenzoate 
• 18962-07-7 4-isobutoxybenzaldehyde 
• 123-08-0 4-hydroxy-benzaldehyde 

Downstream Products

• 21244-29-1 N-(4-isobutoxybenzyl)phthalimide 
• 4734-09-2 1-[4-(2-methylpropyloxy)phenyl]methanamine 
• 14794-52-6 N-hydroxy-2-(4-isobutoxyphenyl)acetamide 
• 706779-91-1 N-(1-methylpiperidin-4-yl)-N-(4-fluorophenylmethyl)-N′-(4-(2-methylpropyloxyl)phenylmethyl)carbamide 
• 706782-28-7 Pimavanserin tartrate 

Relevant articles and documents

Method for synthesizing P-isobutoxybenzylamine

The invention provides a method for synthesizing p-isobutoxy benzylamine. P-hydroxybenzyl alcohol is used as a raw material; the method comprises the following steps: reacting p-hydroxybenzyl alcoholwith halogenated isobutane to obtain p-isobutoxy benzyl alcohol; according to the method, p-isobutoxybenzylamine is obtained by taking p-isobutoxybenzylamine as a raw material and performing a seriesof steps such as chlorination and ammonolysis, so the use of relatively harsh reduction conditions with certain risk is avoided, and the produced p-isobutoxybenzylamine is high in purity and excellentin quality and is an excellent route with industrial prospect.

PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF PIMAVANSERIN

The present disclosure relates to novel, safe and efficient processes for the synthesis of Pimavanserin and salts thereof, as well as novel intermediates that can be used in these processes.

Tartaric acid pimavanserin impurities and preparation method thereof

The invention discloses tartaric acid pimavanserin impurities, namely N-(4-isobutoxy benzyl) diphenyl aminodiphthalate (impurity A), 4-isobutoxy benzyl carbonic acid phenyl ester (impurity B), 4-fluorobenzyl (1-methylpiperidine-4-yl) carbonic acid-4-isobutoxy benzyl ester (impurity C) and N-( isobutoxy benzyl)-N'-(4-fluorobenzyl) urea (impurity E). In addition, the invention further discloses a preparation method of tartaric acid pimavanserin impurities A, B, C and E and an N,N'-bis(4-isobutoxy benzyl) urea (impurity D). Through application of the tartaric acid pimavanserin impurities as reference substances in research on the quality of the tartaric acid pimavanserin intermediate, a crude drug and a compound preparation thereof, a solid foundation is laid for research on the quality of tartaric acid pimavanserin.