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501699-25-8

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501699-25-8 Usage

Physical appearance

White to tan solid
The compound appears as a white to tan solid substance, which may vary in shade depending on the sample's purity and other factors.

Solubility

Soluble in organic solvents
The compound dissolves easily in organic solvents, such as ethanol, acetone, or dichloromethane, which is a key property for its applications in various industries.

Chemical structure

Derivative of indole
2-(4-chloro-phenyl)-2,3-dihydro-1H-indole is derived from the heterocyclic aromatic organic compound indole, which has a core structure consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring.

Potential applications

Pharmaceutical and agrochemical industries
The compound may have potential uses in the pharmaceutical industry for the development of new drugs, as well as in the agrochemical industry for the creation of pesticides, herbicides, or other related products.

Research and development

Possible applications in scientific studies
Due to its unique chemical structure and properties, 2-(4-chloro-phenyl)-2,3-dihydro-1H-indole may be used in research and development for various purposes, such as studying its chemical reactions, exploring its potential applications, or investigating its biological activity.

Context-dependent properties and uses

Specific properties and applications may vary
The specific properties and potential uses of 2-(4-chloro-phenyl)-2,3-dihydro-1H-indole may differ depending on the context in which it is used and the intended application, such as its effectiveness in a particular pharmaceutical formulation or its suitability for a specific agrochemical purpose.

Check Digit Verification of cas no

The CAS Registry Mumber 501699-25-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,1,6,9 and 9 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 501699-25:
(8*5)+(7*0)+(6*1)+(5*6)+(4*9)+(3*9)+(2*2)+(1*5)=148
148 % 10 = 8
So 501699-25-8 is a valid CAS Registry Number.

501699-25-8Relevant articles and documents

Kinetic resolution of indolines through reductive amination of aldehydes by chiral Br?nsted acid

Wang, Yingwei,Li, Guangxun,Liu, Hongxin,Tang, Zhuo,Cao, Yuan,Zhao, Gang

supporting information, p. 2993 - 2996 (2017/07/07)

We have developed a highly efficient and practical strategy for the kinetic resolution of indoline derivatives, involving a chiral Br?nsted acid-catalyzed iminium ion formation and asymmetric transfer hydrogenation cascade process. The kinetic resolution allows the synthesis of 2-substituted N-benzylindolines in good yields with moderate to excellent enantioselectivities.

Chiral phosphoric acid-catalyzed oxidative kinetic resolution of indolines based on transfer hydrogenation to imines

Saito, Kodai,Shibata, Yukihiro,Yamanaka, Masahiro,Akiyama, Takahiko

supporting information, p. 11740 - 11743 (2013/09/02)

The oxidative kinetic resolution of 2-substituted indoline derivatives was achieved by hydrogen transfer to imines by means of a chiral phosphoric acid catalyst. The oxidative kinetic resolution was applicable to racemic alkyl- or aryl-substituted indolines, and the remaining indolines were obtained in good yields with excellent enantioselectivities.

Oxygenation of 2,3-dihydroindoles

Sl?tt, Johnny,Bergman, Jan

, p. 9187 - 9191 (2007/10/03)

Isatogens (3-oxo-3H-indole 1-oxides) possess interesting biological properties and development of a general method to construct these derivatives has now been developed. Indolines (2,3-dihydroindoles) and isatogens have been prepared in an efficient route starting from indoles substituted in position 2. Reduction of the 2-substituted indoles was performed with tin and hydrochloric acid to give racemic indolines, which were converted to isatogens by 3-chloroperoxybenzoic acid (m-CPBA).

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