50372-61-7 Usage
Description
2,3-Dibromo-5-benzoylpyrrole is an organic compound characterized by its unique molecular structure, featuring a pyrrole ring with two bromine atoms at the 2nd and 3rd positions, and a benzoyl group attached at the 5th position. 2,3-Dibromo-5-benzoylpyrrole is known for its potential applications in various fields due to its chemical properties.
Uses
Used in Pharmaceutical Industry:
2,3-Dibromo-5-benzoylpyrrole is used as an intermediate compound for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs with potential therapeutic applications.
Used in Chemical Synthesis:
In the field of organic chemistry, 2,3-Dibromo-5-benzoylpyrrole is used as a building block for the creation of more complex molecules. Its reactive sites, such as the bromine atoms and the benzoyl group, can be further modified to produce a wide range of chemical products.
Used in Research and Development:
2,3-Dibromo-5-benzoylpyrrole is also utilized in research and development settings, where it can be employed to study various chemical reactions and mechanisms. Its unique properties make it an interesting subject for scientific investigation, potentially leading to new discoveries and advancements in the field of chemistry.
In the provided materials, 2,3-Dibromo-5-benzoylpyrrole is specifically used in the preparation of another compound, 4,5-Dibromo-2-benzoylpyrrole, through a series of chemical reactions involving amidation, Friedel-Crafts reaction, and substitution with Br2. This demonstrates its utility as a starting material in the synthesis of complex organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 50372-61-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,3,7 and 2 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 50372-61:
(7*5)+(6*0)+(5*3)+(4*7)+(3*2)+(2*6)+(1*1)=97
97 % 10 = 7
So 50372-61-7 is a valid CAS Registry Number.
50372-61-7Relevant articles and documents
Oxidative Halogenation of Substituted Pyrroles with Cu(II). Part III. Bromination and Chlorination of 2-Benzoylpyrrole
Petruso, S.,Caronna, S.
, p. 355 - 357 (2007/10/02)
The bromination of 2-benzoylpyrrole with copper (II) bromide in the homogenous and heterogenous phase is described, giving 4- and 5-monobromo derivatives whose ratio decreases as the temperature is increased.The same reaction with copper(II) chloride in acetonitrile at 60 deg C produces 5-chloro-2-benzoylpyrrole as the major product. 4,5-Dihalopyrroles in good yields are obtained with an excess of halogenating agent.
Processes for preparing 5-benzoyl-7-halo-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids
-
, (2008/06/13)
5-benzoyl-7-halo-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids, represented by the formula STR1 and the pharmaceutically acceptable non-toxic esters and salts thereof, wherein: R is hydrogen or lower alkyl; X is hydrogen, lower alkyl, lower alkoxyl, lower alkoxycarbonyl, carboxyl, lower alkylcarbonyl, sulfonic acid, sulfonic acid alkyl ester, fluoro, chloro, or bromo; and Y is chloro or bromo, which are novel, and 5-benzoyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids which are represented by the formula STR2 wherein X and R are as above defined except that X cannot be chloro or bromo, are prepared by decarboxylation of the corresponding 1,1 dicarboxylates. Intermediates in said preparation are also disclosed.
