50438-75-0

Basic information

• Product Name: 4-(DIMETHYLAMINO)PHENETHYL ALCOHOL
• Synonyms: 4-(DIMETHYLAMINO)PHENETHYL ALCOHOL, 99+%;Benzeneethanol, 4-(dimethylamino)-;4-(Dimethylamino)benzeneethanol;p-(Dimethylamino)phenethyl alcohol;2-(4-Dimetylaminophenyl)ethanol;Ccris 987;4-(N,N-dimethylamino)benzeneethanol;2-(4-(Dimethylamino)
• CAS NO: 50438-75-0
• Molecular Formula: C₁₀H₁₅NO
• Molecular Weight: 165.23
• Mol File: 50438-75-0.mol
• Article Data: 7

Chemical Properties

• Melting Point: 54-58 °C(lit.)
• Boiling Point: 284.5°Cat760mmHg
• Flash Point: 136.5°C
• Appearance: White to light brown/Crystalline Powder
• Density: 1.047g/cm³
• Vapor Pressure: 0.00139mmHg at 25°C
• Refractive Index: 1.568
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 15.07±0.10(Predicted)
• BRN: 2717032
• CAS DataBase Reference: 4-(DIMETHYLAMINO)PHENETHYL ALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(DIMETHYLAMINO)PHENETHYL ALCOHOL(50438-75-0)
• EPA Substance Registry System: 4-(DIMETHYLAMINO)PHENETHYL ALCOHOL(50438-75-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 50438-75-0(Hazardous Substances Data)

Usage

Description

4-(DIMETHYLAMINO)PHENETHYL ALCOHOL, also known as 2-[4-(Dimethylamino)phenyl]ethanol, is an organic compound with a dimethylamino group attached to a phenethyl alcohol structure. It is known for its potential applications in various fields, particularly in the study and development of materials and processes.

Uses

Used in Medical Research:
4-(DIMETHYLAMINO)PHENETHYL ALCOHOL is used as an accelerator in the investigation of the curing process of bone cement at the molecular level through electron spin resonance (ESR) spectroscopy. This application aids in understanding the mechanisms and efficiency of bone cement hardening, which is crucial for its performance in orthopedic and dental applications.
Used in Dental Applications:
In the dental industry, 4-(DIMETHYLAMINO)PHENETHYL ALCOHOL serves as a component to compare the efficiency of different camphorquinone (CQ)/amine photo-initiating systems for the photopolymerization of a model dental resin. This comparison is essential for optimizing dental resin formulations, ensuring effective and efficient curing processes that lead to better dental restorations and patient outcomes.

InChI:InChI=1/C10H15NO/c1-11(2)10-5-3-9(4-6-10)7-8-12/h3-6,12H,7-8H2,1-2H3

Upstream product

• 100-10-7 4-dimethylamino-benzaldehyde 
• 1703-46-4 N,N-dimethyl-4-hydroxymethylaniline 
• 66379-84-8 2,2,2-trichloro-1-[4-(dimethylamino)phenyl]ethan-1-ol 
• 17078-28-3 2-[4-(dimethylamino)phenyl]acetic acid 
• 2039-80-7 N,N-dimethy-4-vinylaniline 
• 50-00-0 formaldehyd 
• 100-27-6 2-(4-nitrophenyl)ethanol 

Downstream Products

• 281678-05-5 2-[4-(dimethylamino)phenyl]ethyl methanesulfonate 
• 524743-26-8 2-[2-(4-N,N-dimethylaminophenyl)-ethyl]-isoindole-1,3-dione 
• 1148144-58-4 4-((1H-benzimidazol-2-yl)methyl)-N,N-dimethylaniline 
• 1609169-96-1 N-benzyl-2-(4-(dimethylamino)phenyl)acetamide 
• 56153-01-6 p-(N,N-dimethylamino)phenethyl bromide 
• 56153-00-5 1-chloro-2-(4-dimethylaminophenyl)ethane 
• 139670-57-8 2-(4-dimethylaminophenyl)ethyl tosylate 
• 116308-57-7 2-(4-dimethylaminophenyl)ethyl acetoacetate 
• 103798-03-4 2-(4-dimethylaminophenyl)-N,N-dimethylethanamine 

Relevant articles and documents

OXADIAZOLONES AS TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS

The invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.

α-Alkylidene-γ-butyrolactone synthesis via one-pot C-H insertion/olefination: substrate scope and the total synthesis of (±)-cedarmycins A and B

Abstract A system for the synthesis of α-alkylidene-γ-butyrolactones via a one-pot C-H insertion/olefination sequence is described. The process is based on the rhodium catalysed C-H insertion reaction of α-diazo-α-(diethoxyphosphoryl)acetates. The mild reaction conditions, operational simplicity and ready availability of starting materials are all key features. A wide range of successful reaction systems are reported (41 examples) highlighting the generality of the method. The application of this method in the total synthesis of the natural products (±)-cedarmycins A and B is also described.

ARTEMISININ-BASED PEROXIDE COMPOUNDS AS BROAD SPECTRUM ANTI-INFECTIVE AGENTS

Described herein is the synthesis, bioassay results and utility of new C-9 and C-10 substituted artemisinin derivatives with easily functionalizable groups attached to the artemisinin skeleton through carbon chain or heteroatoms. Described also is the demonstration of this class of compounds for their broad-spectrum anti-parasitic activity. Certain of these analogs possess noticeable cytotoxicity deliberately focused on treatment of cancerous diseases.