5068-21-3

Basic information

• Product Name: (4-HYDROXYPHENYL)DIPHENYLPHOSPHINE
• Synonyms: DIPHENYL-(4-HYDROXYPHENYL)PHOSPHINE;(4-HYDROXYPHENYL)DIPHENYLPHOSPHINE;(4-HYDROCYPHENYL)DIPHENYLPHOSPHINE, 99%;(p-hydroxyphenyl)diphenylphosphine;4-(Diphenylphosphino)phenol
• CAS NO: 5068-21-3
• Molecular Formula: C₁₈H₁₅OP
• Molecular Weight: 278.28
• Mol File: 5068-21-3.mol
• Article Data: 20

Chemical Properties

• Melting Point: 105-110 °C(lit.)
• Boiling Point: 406.8°C at 760 mmHg
• Flash Point: 199.8°C
• Appearance: /
• Vapor Pressure: 3.36E-07mmHg at 25°C
• PKA: 9.32±0.13(Predicted)
• CAS DataBase Reference: (4-HYDROXYPHENYL)DIPHENYLPHOSPHINE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-HYDROXYPHENYL)DIPHENYLPHOSPHINE(5068-21-3)
• EPA Substance Registry System: (4-HYDROXYPHENYL)DIPHENYLPHOSPHINE(5068-21-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 5068-21-3(Hazardous Substances Data)

Usage

Description

(4-HYDROXYPHENYL)DIPHENYLPHOSPHINE, with the chemical formula C18H15OP, is an organophosphorus compound that serves as a phosphine ligand in coordination chemistry and organometallic chemistry. (4-HYDROXYPHENYL)DIPHENYLPHOSPHINE features a hydroxyphenyl group and two phenyl groups attached to a central phosphorus atom, making it a versatile and significant tool for the development of new catalytic processes and the study of metal-ligand interactions.

Uses

Used in Coordination Chemistry:
(4-HYDROXYPHENYL)DIPHENYLPHOSPHINE is used as a phosphine ligand for enhancing the stability and reactivity of metal complexes. Its unique structure allows for the fine-tuning of the electronic and steric properties of the complexes, which is crucial for optimizing their performance in various chemical reactions.
Used in Organometallic Chemistry:
In organometallic chemistry, (4-HYDROXYPHENYL)DIPHENYLPHOSPHINE is used as a ligand to form organometallic complexes. These complexes are essential in catalytic reactions and can be employed in the synthesis of various organic compounds, contributing to the advancement of synthetic chemistry.
Used in Catalytic Reactions:
(4-HYDROXYPHENYL)DIPHENYLPHOSPHINE is used as a ligand in catalytic reactions to improve the efficiency and selectivity of the process. Its presence in the catalyst system can lead to better control over the reaction pathways, resulting in higher yields and more environmentally friendly processes.
Used in the Synthesis of Organometallic Complexes:
(4-HYDROXYPHENYL)DIPHENYLPHOSPHINE is used as a key component in the synthesis of various organometallic complexes, which have applications in areas such as homogeneous catalysis, materials science, and pharmaceuticals. The organometallic complexes synthesized using (4-HYDROXYPHENYL)DIPHENYLPHOSPHINE can exhibit unique properties and reactivities due to the presence of this versatile ligand.

InChI:InChI=1/C18H15OP/c19-15-11-13-18(14-12-15)20(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-14,19H

Upstream product

• 793-43-1 (4-Hydroxyphenyl)diphenylphosphine oxide 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 1499-21-4 Diphenylphosphinic chloride 
• 795-44-8 4-(diphenylphosphoryl)benzonitrile 
• 67963-68-2 t-butyldimethylsilyl-4-bromophenol 
• 1079-66-9 chloro-diphenylphosphine 
• 36603-49-3 4-(tetrahydropyran-2'-yloxy)-1-bromobenzene 
• 937378-85-3 [(η⁶-p-cymene)RuCl₂(κP-PPh₂(4-C₆H₄OH))] 
• 896-89-9 (4-methoxyphenyl)diphenylphosphane 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 106-41-2 4-bromo-phenol 
• 528609-62-3 (4-hydroxyphenyl)diphenylphosphine borane 
• 238403-27-5 4-(tert-butyldimethylsiloxy)phenyldiphenylphosphine 
• 540-38-5 p-Iodophenol 

Downstream Products

• 252245-48-0 W(CO)5(4-hydroxyphenyl diphenylphosphine) 
• 937378-87-5 [(1,5-cyclooctadiene)RhCl(PPh₂C₆H₄OH)] 
• 937378-85-3 [(η⁶-p-cymene)RuCl₂(κP-PPh₂(4-C₆H₄OH))] 
• 1353567-03-9 1-(4-diphenylphosphinophenolato)-2,8,9-trioxa-5-aza-3,3,7,7,10,10-hexamethylstannatricyclo[3.3.3.0(1.5)]undecane 
• 528609-62-3 (4-hydroxyphenyl)diphenylphosphine borane 
• 252245-52-6 (OC₆H₄P(C₆H₅)2)2PN(NP(OC₆H₄)2)2 

Relevant articles and documents

Ultrashort Hδ+?Hδ?intermolecular distance in a supramolecular system in the solid state

Herein we report experimental evidence for the shortest intermolecular distance reported for two electronically-different hydrogen atoms in the solid state. The Hδ+?Hδ?non-covalent interaction was studied using theoretical calculatio

Phosphine boranes as less hydrophobic building blocks than alkanes and silanes: Structure-property relationship and estrogen-receptor-modulating potency of 4-phosphinophenol derivatives

Increasing structural options in medicinal chemistry is important for the development of novel and distinctive drug candidates. In this study, we focused on phosphorus-containing functionalities. We designed and synthesized a series of phosphinophenol der

Preparation method of amphiphilic PN = PS type phosphorus-containing crown macromolecular nano-micelle and application of crown macromolecular nano-micelle as drug carrier

The invention relates to a preparation method of amphipathic PN = PS type phosphorus-containing crown macromolecule nano-micelle and application of the crown macromolecular nano-micelle as a drug carrier. The obtained amphipathic phosphorus-containing crown macromolecule can be self-assembled into the nano-micelle in water, and a hydrophobic drug can be embedded into a hydrophobic cavity in the nano-micelle to form a stable compound. The method disclosed by the invention is simple, high in reaction controllability, easy in operation and separation, low in cost, uniform in final product molecular weight and commercialized in raw material source, and has a good development prospect.