50901-42-3

Basic information

• Product Name: PYRIDAZINE-4-CARBALDEHYDE
• Synonyms: PYRIDAZINE-4-CARBALDEHYDE;RARECHEM AM LA 0037;Pyridazine-4-carboxaldehyde;4-Formylpyridazine;4-Pyridazinecarboxaldehyde;4-Pyridazinecarboxaldehyd...;4-Pyridazinecarbaldehyde;Pyridazinde-4-carbaldehyde
• CAS NO: 50901-42-3
• Molecular Formula: C₅H₄N₂O
• Molecular Weight: 108.1
• Mol File: 50901-42-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 70 °C (sublm)
• Boiling Point: 300.361 °C at 760 mmHg
• Flash Point: 139.901 °C
• Appearance: /
• Density: 1.235 g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.581
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 0.83±0.10(Predicted)
• CAS DataBase Reference: PYRIDAZINE-4-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: PYRIDAZINE-4-CARBALDEHYDE(50901-42-3)
• EPA Substance Registry System: PYRIDAZINE-4-CARBALDEHYDE(50901-42-3)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 50901-42-3(Hazardous Substances Data)

Usage

General Description

Pyridazine-4-carbaldehyde is a chemical compound with the molecular formula C5H4N2O. It is a heterocyclic compound containing a pyridazine ring with an aldehyde functional group attached to the 4th carbon atom. Pyridazine-4-carbaldehyde is commonly used as a building block in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. It is also used as an intermediate in the manufacturing of dyes and other fine chemicals. Pyridazine-4-carbaldehyde has been studied for its potential biological activities, including its antibacterial and antifungal properties. Additionally, it is utilized in the preparation of various coordination complexes for applications in materials science and catalysis.

InChI:InChI=1/C5H4N2O/c8-4-5-1-2-6-7-3-5/h1-4H

Upstream product

• 1120-88-3 4-methylpyridazine 
• 77709-03-6 4-symm.Trioxanylpyridazin 
• 39816-19-8 4-styrylpyridazine 

Downstream Products

• 85226-66-0 2-(4-pyridazinyl)benzothiazole 
• 1417700-03-8 C₂₅H₃₀N₄O₃ 
• 187266-25-7 (4-Methoxy-phenyl)-[1-pyridazin-4-yl-meth-(E)-ylidene]-amine 
• 34231-77-1 methyl pyridazine-4-carboxylate 
• 50901-46-7 Methyl 4-pyridazinyl ketone 
• 50901-50-3 pyridazine-4-carbaldehyde oxime 

Relevant articles and documents

BENZIMIDAZOLE DERIVATIVES AND METHODS OF USE THEREOF

The present invention relates to compounds of formula (I); compositions comprising the compounds, and methods of using the compounds to treat or prevent pain, diabetes, a diabetic complication, impaired glucose tolerance (IGT) or impaired fasting glucose

INDOLE DERIVATIVES USEFUL AS HISTAMINE H3 ANTAGONISTS

Disclosed are novel compounds of the formula I wherein M1 is CH or N and M2 is C(R3) or N; R1 is optionally substituted indolyl or an aza derivative thereof; R2 is optionally substituted aryl or heteroaryl; and the remaining variables are as defined in the specification. Also disclosed are pharmaceutical compositions comprising the compounds of formula I. Also disclosed are methods of treating various diseases or conditions, such as, for example, allergy, allergy-induced airway responses, and congestion (e.g., nasal congestion) using the compounds of Formula I. Also disclosed are methods of treating various diseases or conditions, such as, for example, allergy, allergy-induced airway responses, and congestion (e.g., nasal congestion) using the compounds of formula I in combination with a H1 receptor antagonist.

Substitution des 1,2-Diazinsystems mit symm.Trioxanylradikalen; ein Zugang zu Pyridazincarbaldehyden. 13. Mitteilung ueber Pyridazine

Pyridazine (1) and 3-methylpyridazine (5) selectively are attacked by symm.trioxanyl radicals in positions 4 and/or 5 yielding 2, 3, 6, 7, 8, while 4-methylpyridazine (10) under similar conditions reacts to give not only C-5 substitution product 11, but also 3- and/or 6-trioxanylsubstituted methylpyridazines 12-15.The structures of the isomeric compounds were confirmed on basis of pmr-data.By hydrolysis of 6, 11, and 12 the unknown formylmethylpyridazines 9, 16 and 17 were prepared.Compound 16 was found to undergo intermolecular aldol-type addition easily yielding lactol 18.Synthesis of pyridazinecarboxaldehyde (4) starting from 1 is presented.