5098-14-6 Usage
Description
AMINOMALONONITRILE P-TOLUENESULFONATE is an organic compound that serves as a reagent in various chemical synthesis processes. It is characterized by its unique structure, which allows it to participate in a range of reactions, making it a valuable component in the synthesis of different organic compounds.
Uses
Used in Pharmaceutical Synthesis:
AMINOMALONONITRILE P-TOLUENESULFONATE is used as a reagent for the synthesis of 1-substituted 5-amino-4-cyano-2-hydroxyimidazoles, which are important intermediates in the development of pharmaceutical compounds. Its role in this synthesis process is crucial for creating new and potentially effective drugs.
Used in Organic Chemistry Research:
In the field of organic chemistry, AMINOMALONONITRILE P-TOLUENESULFONATE is used as a reagent for diazonamide synthesis via heck endocyclization. This application highlights its versatility and utility in creating complex organic molecules, which can be further explored for their potential applications in various industries.
Used in Drug Development:
AMINOMALONONITRILE P-TOLUENESULFONATE may have implications for developing IκB Kinase-β inhibitors. This suggests that the compound could play a role in the creation of new drugs targeting specific biological pathways, potentially leading to treatments for various diseases and conditions.
Overall, AMINOMALONONITRILE P-TOLUENESULFONATE is a versatile reagent with applications in pharmaceutical synthesis, organic chemistry research, and drug development. Its unique properties and ability to participate in various chemical reactions make it an important tool in the creation of new and innovative compounds.
Purification Methods
It forms colourless crystals on recrystallisation from MeCN (1.8g in 100mL) using activated charcoal. Wash the crystals with dry Et2O and dry them at 25o/1mm. Recovery is ~80%. [Ferris et al. Org Synth Coll Vol V 32 1973.]
Check Digit Verification of cas no
The CAS Registry Mumber 5098-14-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,0,9 and 8 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 5098-14:
(6*5)+(5*0)+(4*9)+(3*8)+(2*1)+(1*4)=96
96 % 10 = 6
So 5098-14-6 is a valid CAS Registry Number.
InChI:InChI=1/C7H8O3S.C3H3N3/c1-6-2-4-7(5-3-6)11(8,9)10;4-1-3(6)2-5/h2-5H,1H3,(H,8,9,10);3H,6H2
5098-14-6Relevant articles and documents
A New Synthesis of Aminomalononitrile Tosylate
Taylor, Edward C.,Sun, Jung-Hui
, p. 801 - 802 (1980)
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O-(DIPHENYLPHOSPHINYL)HYDROXYLAMINE: A NEW REAGENT FOR ELECTROPHILIC C-AMINATION
Colvin, Ernest W.,Kirby, Gordon W.,Wilson, Arthur C.
, p. 3835 - 3836 (2007/10/02)
O-(Diphenylphosphinyl)hydroxylamine efficiently aminates a variety of stabilised carbanions and certain Grignard reagents.