50986-84-0

Basic information

• Product Name: 4-(trifluoromethyl)benzenesulfinyl chloride
• Synonyms: 4-(trifluoromethyl)benzenesulfinyl chloride
• CAS NO: 50986-84-0
• Molecular Weight: 228.622
• Mol File: 50986-84-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-(trifluoromethyl)benzenesulfinyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(trifluoromethyl)benzenesulfinyl chloride(50986-84-0)
• EPA Substance Registry System: 4-(trifluoromethyl)benzenesulfinyl chloride(50986-84-0)

Safety Data

• Hazardous Substances Data: 50986-84-0(Hazardous Substances Data)

Upstream product

• 18715-45-2 4-trifluoromethylphenyl disulfide 
• 825-83-2 4-trifluoromethylbenzenethiol 
• 402-43-7 p-trifluoromethylphenyl bromide 

Downstream Products

• 829-70-9 4-(trifluoromethyl)benzenesulfinic acid 
• 1026288-18-5 C₁₄H₉Cl₂F₃N₂O₂S 
• 187342-51-4 C₁₄H₁₀ClF₃N₂O₂S 
• 233752-03-9 C₁₉H₃₂F₃NO₂SSi 
• 233752-02-8 C₁₃H₁₈F₃NO₂S 
• 233752-01-7 C₁₃H₁₈F₃NO₂S 
• 233751-99-0 4-Trifluoromethyl-benzenesulfinic acid ((R)-1-hydroxymethyl-2-methyl-propyl)-amide 
• 233752-00-6 4-isopropyl-2-(4-trifluoromethyl-phenyl)-4H,5H-2λ⁴-[1,2,3]oxathiazole 2-oxide 
• 233751-98-9 4-Trifluoromethyl-benzenesulfinic acid ((R)-2-methyl-1-trimethylsilanyloxymethyl-propyl)-amide 
• 1026629-55-9 4-Trifluoromethyl-benzenesulfinyl isocyanate 

Relevant articles and documents

Sulfoxide ligand metal catalyzed oxidation of olefins

The enantioselective synthesis of isochroman motifs has been accomplished via Pd(II)-catalyzed allylic C—H oxidation from terminal olefin precursors. Critical to the success of this goal was the development and utilization of a novel chiral aryl sulfoxide-oxazoline (ArSOX) ligand. The allylic C—H oxidation reaction proceeds with the broadest scope and highest levels asymmetric induction reported to date (avg. 92% ee, 13 examples ≥90% ee). Additionally, C(sp3)-N fragment coupling reaction between abundant terminal olefins and N-triflyl protected aliphatic and aromatic amines via Pd(II)/sulfoxide (SOX) catalyzed intermolecular allylic C—H amination is disclosed. A range of 52 allylic amines are furnished in good yields (avg. 76%) and excellent regio- and stereoselectivity (avg. >20:1 linear:branched, >20:1 E:Z). For the first time, a variety of singly activated aromatic and aliphatic nitrogen nucleophiles, including ones with stereochemical elements, can be used in fragment coupling stiochiometries for intermolecular C—H amination reactions.

C2-symmetric chiral disulfoxide ligands in rhodium-catalyzed 1,4-addition: From ligand synthesis to the enantioselection pathway

A family of chiral C2-symmetric disulfoxide ligands possessing biaryl atropisomeric backbones has been synthesized by using the Andersen methodology. Complete characterization includes X-ray crystallographic studies of all ligands and some of t