51-64-9 Usage
Description
D-AMPHETAMINE HYDROCHLORIDE, also known as D-Amphetamine Hydrochloride, is a 1-phenylpropan-2-amine with an S configuration. It is a more active isomer of Amphetamine and is classified as a controlled substance (stimulant). D-AMPHETAMINE HYDROCHLORIDE is known for its central nervous system (CNS) stimulating properties and anorexic effects. It works by inducing the release of catecholamines and serotonin, displacing the monoamines from their vesicular storage sites, and blocking catecholamine reuptake.
Uses
Used in Pharmaceutical Industry:
D-AMPHETAMINE HYDROCHLORIDE is used as a CNS stimulant for treating conditions such as attention deficit hyperactivity disorder (ADHD) and narcolepsy. It is also used as an anorexic agent to suppress appetite, which can be beneficial for weight loss management.
Used in Research and Development:
D-AMPHETAMINE HYDROCHLORIDE is used as a research compound for studying the effects of stimulants on the central nervous system and their potential applications in various medical conditions.
Brand Names:
Some of the brand names for D-AMPHETAMINE HYDROCHLORIDE include Dexampex (Teva), Dexedrine (GlaxoSmithKline), Dextrostat (Shire), Ferndex (Ferndale), Adiparthrol, Afatin, Amfe-dyn, Amphaetex, Bipheramine, Curban, D-amfetasul, Dexadrine, Dexamed, Dexedrina, Dexten, Dextro-profetamine, Drinamyl, Durophet-m, Maxiton, Mephadexamine-r, Mephadexamin-r, Obetrol, Obotan, Proptan, Robese, Simpamina d, Steladex, Stil-2, and Synatan.
World Health Organization (WHO)
Schedule II of the 1971 Convention on Psychotropic Substances. See WHO
comment for amfetamine.
(Reference: (UNCPS2) United Nations Convention on Psychotropic Substances (II),
, , 1971)
Safety Profile
Poison by ingestion,
subcutaneous, intravenous, and
intraperitoneal routes. Experimental
reproductive effects. Chronic exposure
causes central nervous system damage and
blood-pressure effects. When heated to
decomposition it emits toxic NOx. See other
amphetamine entries.
Check Digit Verification of cas no
The CAS Registry Mumber 51-64-9 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 5 and 1 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 51-64:
(4*5)+(3*1)+(2*6)+(1*4)=39
39 % 10 = 9
So 51-64-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3/t8-/m0/s1
51-64-9Relevant articles and documents
ASPARAGINE DERIVATIVES AND METHODS OF USE THEREOF
-
, (2021/12/31)
The present invention relates to compounds of formulas (A) and (I), pharmaceutically acceptable salts thereof, and solvates of any of them, pharmaceutical compositions comprising them, methods of preparation thereof, intermediate compounds useful for the preparation thereof, and methods of treatment or prophylaxis of diseases, in particular cancer, such as colorectal cancer, using these. (A) (I)
Direct Access to Primary Amines from Alkenes by Selective Metal-Free Hydroamination
Du, Yi-Dan,Chen, Bi-Hong,Shu, Wei
supporting information, p. 9875 - 9880 (2021/03/29)
Direct and selective synthesis of primary amines from easily available precursors is attractive yet challenging. Herein, we report the rapid synthesis of primary amines from alkenes via metal-free regioselective hydroamination at room temperature. Ammonium carbonate was used as ammonia surrogate for the first time, allowing for efficient conversion of terminal and internal alkenes into linear, α-branched, and α-tertiary primary amines under mild conditions. This method provides a straightforward and powerful approach to a wide spectrum of advanced, highly functionalized primary amines which are of particular interest in pharmaceutical chemistry and other areas.
ISOINDOLINE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION OF ISOINDOLINE COMPOUND
-
Paragraph 0313; 0317, (2021/10/22)
The present invention relates to an isoindoline compound as represented by general formula (I) and used as a CRBN regulator, and a preparation method, a pharmaceutical composition, and an application of the isoindoline compound. Specifically, a class of polysubstituted isoindoline compound provided in the present invention, as a class of CRL4CRBN E3 ubiquitin ligase regulator having a novel structure, has good anti-tumor activity and immunoregulatory activity, and can be used for preparing drugs for treating diseases associated with a CRL4CRBN E3 ubiquitin ligase.