51171-02-9

Basic information

• Product Name: methyl 3-bromopyrazine-2-carboxylate
• Synonyms: methyl 3-bromopyrazine-2-carboxylate;3-BroMo-pyrazine-2-carboxylic acid Methyl ester;Methyl 2-bromopyrazine-3-carboxylate;Methyl 3-BroMo-2-pyrazinecarboxylate;3-bromo-2-Pyrazinecarboxylic acid methyl ester;Pyrazinecarboxylic acid, 3-bromo-, methyl ester
• CAS NO: 51171-02-9
• Molecular Formula: C₆H₅BrN₂O₂
• Molecular Weight: 217.03
• Product Categories: alkyl bromide| carboxylic ester
• Mol File: 51171-02-9.mol
• Article Data: 18

Chemical Properties

• Melting Point: 44℃
• Boiling Point: 264.7±35.0℃ (760 Torr)
• Flash Point: 113.9±25.9℃
• Appearance: /
• Density: 1.669±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.01mmHg at 25°C
• Refractive Index: 1.558
• Storage Temp.: 2-8°C
• PKA: -2.41±0.10(Predicted)
• CAS DataBase Reference: methyl 3-bromopyrazine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-bromopyrazine-2-carboxylate(51171-02-9)
• EPA Substance Registry System: methyl 3-bromopyrazine-2-carboxylate(51171-02-9)

Safety Data

• Hazardous Substances Data: 51171-02-9(Hazardous Substances Data)

Usage

General Description

Methyl 3-bromopyrazine-2-carboxylate is a chemical compound with the formula C8H7BrN2O2. It is a methyl ester derivative of 3-bromopyrazine-2-carboxylic acid, which is a monocarboxylic acid. methyl 3-bromopyrazine-2-carboxylate is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used as a building block in organic synthesis, specifically in the production of pyrazine-based heterocycles. Methyl 3-bromopyrazine-2-carboxylate is a white, crystalline solid that is soluble in organic solvents such as methanol and acetone. Its chemical properties make it a versatile and important compound in the field of medicinal and agricultural chemistry.

InChI:InChI=1/C6H5BrN2O2/c1-11-6(10)4-5(7)9-3-2-8-4/h2-3H,1H3

Upstream product

• 5424-01-1 3-aminopyrazinoic acid 
• 16298-03-6 Methyl 3-amino-2-pyrazinecarboxylate 

Downstream Products

• 1415407-08-7 C₂₀H₁₅Cl₂N₃O₂ 
• 885685-66-5 lithium 3-(2-tritylsulfanylethylamino)pyrazine-2-carboxylate 
• 1351237-96-1 N-(5-(3-(2-cyanopropan-2-yl)benzamido)-2-methylphenyl)-3-ethoxythieno[2,3-b]pyrazine-6-carboxamide 
• 40155-20-2 methyl 3-methoxypyrazine-2-carboxylate 
• 89109-19-3 2-anilino-3-carbomethoxypyrazine 
• 455265-99-3 (3-Methyl-pyrazin-2-yl)-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-ylmethyl]-amine 
• 784155-40-4 methyl 3-[(1-benzylpiperidin-4-yl)amino]pyrazine-2-carboxylate 
• 6164-77-8 pyrazine-2,3-dicarboxylic acid dimethyl ester 
• 151322-82-6 methyl 3-biphenyl-4-yl>methyl>amino>pyrazine-2-carboxylate 

Relevant articles and documents

THIENO (2, 3B) PYRAZINE COMPOUNDS AS B-RAF INHIBITORS

The invention relates to compounds according to general Formula (I) or a pharmaceutically acceptable salt thereof. The compounds can be used for the treatment of cancer.

THIENO (2, 3B) PYRAZINE COMPOUNDS AS B - RAF INHIBITORS

The invention relates to compounds according to general Formula (I) or a pharmaceutically acceptable salt thereof. The compounds can be used for the treatment of cancer.

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