51241-41-9

Basic information

• Product Name: 1-methoxy-3-(1-methylethoxy)benzene
• Synonyms: Benzene, 1-methoxy-3-(1-methylethoxy)-; Isopropyl m-methoxyphenyl ether
• CAS NO: 51241-41-9
• Molecular Formula: C₁₀H₁₄O₂
• Molecular Weight: 166.217
• Mol File: 51241-41-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 231.9°C at 760 mmHg
• Flash Point: 82.7°C
• Density: 0.973g/cm³
• Vapor Pressure: 0.0921mmHg at 25°C
• Refractive Index: 1.483
• CAS DataBase Reference: 1-methoxy-3-(1-methylethoxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methoxy-3-(1-methylethoxy)benzene(51241-41-9)
• EPA Substance Registry System: 1-methoxy-3-(1-methylethoxy)benzene(51241-41-9)

Safety Data

• Hazardous Substances Data: 51241-41-9(Hazardous Substances Data)

Usage

Molecular weight

270.33 g/mol The relative molecular mass of isoeugenol, based on the atomic weights of its constituent elements.

Phenylpropanoid

A subclass of organic compounds This indicates that isoeugenol belongs to a specific group of compounds derived from phenylpropane, which is a precursor in the biosynthesis of many secondary plant metabolites.

Naturally occurring in essential oils

Basil, clove, and ylang-ylang Isoeugenol can be found in the essential oils extracted from these plants, contributing to their unique aromas and properties.

Sweet, spicy aroma

The characteristic scent of isoeugenol This describes the pleasant and warm fragrance of isoeugenol, which is often used in flavoring and perfumery applications.

Flavoring agent

Used in foods and beverages Isoeugenol is added to various food and drink products to impart its distinct flavor and aroma.

Antimicrobial and antioxidant properties

Isoeugenol exhibits these biological activities This means that isoeugenol can help inhibit the growth of microorganisms and protect against oxidative damage, making it a valuable ingredient in cosmetic and personal care products.

Skin sensitization

Can cause allergic reactions in some individuals This potential side effect of isoeugenol may lead to skin irritation or allergic contact dermatitis in certain people.

Regulated by health authorities

受限于某些司法管辖区的法规 In some regions, the use of isoeugenol in products is monitored and regulated by health authorities to ensure consumer safety.

Upstream product

• 5419-55-6 Triisopropyl borate 
• 52509-81-6 potassium 4-methoxybenzoate 
• 100-09-4 4-methoxybenzoic acid 
• 2398-37-0 3-methoxyphenyl bromide 
• 683-60-3 sodium isopropylate 
• 75-30-9 2-iodo-propane 
• 150-19-6 O-methylresorcine 
• 456-49-5 1-fluoro-3-methoxybenzene 
• 67-63-0 isopropyl alcohol 
• 151-10-0 1,3-Dimethoxybenzene 

Downstream Products

• 2150-41-6 methyl 2, 4-dimethoxybenzoate 
• 2065-27-2 methyl 2,6-dimethoxybenzoate 
• 1160293-55-9 2-bromo-3-isopropoxyanisole 
• 1160293-45-7 2-iodo-3-isopropoxyanisole 
• 86636-10-4 3,5-Dinitro-benzoic acid 3-isopropoxy-phenyl ester 
• 68792-12-1 3-isopropoxyphenol 
• 79128-13-5 4-isopropoxy-2-methoxybenzoic acid 

Relevant articles and documents

Practical Ligand-Free Copper-Catalysed Short-Chain Alkoxylation of Unactivated Aryl Bromides

An efficient and practical short-chain alkoxylation of unactivated aryl bromides has been developed with special attention focussed on the applicability of the reaction. Sodium alkoxide is used as the nucleophile, and the corresponding alcohol as the solvent. The reaction requires neither precious metals nor organic ligands. It uses a catalytic system consisting of copper(I) bromide as a catalyst, the corresponding alkyl formate as a noncontaminating cocatalyst, and lithium chloride as an additive. A wide range of substrates and test cases highlight the synthetic utility of the approach. Considering the commercial accessibility and affordability of the feedstocks, this protocol shows promise as a new alternative for the sustainable preparation of aryl alkyl ethers.

Synthesis of aryl ethers from aromatic carboxylic acids

A silver/copper bimetallic catalyst system promotes the decarboxylative Chan-Evans-Lam alkoxylation of ortho-substituted aromatic carboxylate salts with tetraalkyl orthosilicates or triaryl borates. Non-ortho-substituted carboxylates are alkoxylated via an ortho-C-H-alkoxylation with concomitant cleavage of the carboxylate directing group via protodecarboxylation. This way, meta-substituted carboxylates are converted into para-substituted alkoxyarenes and vice versa. The combined processes provide a convenient synthetic entry to the important class of aromatic ethers from widely available carboxylic acids.

Practical synthesis of aromatic ethers by SNAr of fluorobenzenes with alkoxides

Aromatic fluorines have been substituted by alkoxides in a variety of activated and unactivated aromatic systems.