51460-32-3

Basic information

• Product Name: 1-(5-Aminopyridin-2-yl)ethanone
• Synonyms: 1-(5-Aminopyridin-2-yl)ethanone;Ethanone, 1-(5-amino-2-pyridinyl)-;1-(5-aMino-2-pyridinyl)-Ethanone;1-(5-aminopyridin-2-yl)ethanone hcl
• CAS NO: 51460-32-3
• Molecular Formula: C₇H₈N₂O
• Molecular Weight: 136.15
• Mol File: 51460-32-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 336.726 °C at 760 mmHg
• Flash Point: 157.446 °C
• Appearance: /
• Density: 1.169 g/cm³
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 3.93±0.10(Predicted)
• CAS DataBase Reference: 1-(5-Aminopyridin-2-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-Aminopyridin-2-yl)ethanone(51460-32-3)
• EPA Substance Registry System: 1-(5-Aminopyridin-2-yl)ethanone(51460-32-3)

Safety Data

• Hazardous Substances Data: 51460-32-3(Hazardous Substances Data)

Usage

General Description

1-(5-Aminopyridin-2-yl)ethanone, also known as 5-Amino-2-pyridinecarbaldehyde, is an organic compound with the molecular formula C7H8N2O. It is a yellow solid with a melting point of 92-95 °C. This chemical is used in the synthesis of various pharmaceuticals and organic compounds. It has also been studied for its potential use in the treatment of various medical conditions, including cancer and neurological disorders. 1-(5-Aminopyridin-2-yl)ethanone is a versatile compound with a range of potential applications in both the pharmaceutical and chemical industries.

Upstream product

• 676-58-4 methylmagnesium chloride 
• 55338-73-3 5-amino-2-cyanopyridine 
• 100367-55-3 5-nitropyridine-2-carbonitrile 
• 4487-59-6 2-bromo-5-nitropyridine 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 858599-23-2 tert-butyl (6-acetylpyridin-3-yl)carbamate 
• 1566584-23-3 2-(2-(2-(2-((6-(1-aminoethyl)pyridin-3-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)ethyl)phenyl)acetamide 
• 1566585-47-4 2-(2-(2-(2-((6-acetylpyridin-3-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)ethyl)phenyl)acetamide 
• 1566585-46-3 2-(2-((2-((6-acetylpyridin-3-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)ethynyl)phenyl)acetamide 
• 1566543-07-4 1-(2-(2-(2-((6-acetylpyridin-3-yl)amino)-5-chloropyrimidin-4-yl)ethyl)phenyl)cyclopropanecarboxamide 

Relevant articles and documents

JAK1 SELECTIVE KINASE INHIBITOR

Disclosed herein are compounds of Formula (I), and pharmaceutically acceptable salts thereof, that are useful as JAK kinase inhibitors. Also disclosed are pharmaceutical compositions comprising one or more compounds of Formula (I), and methods of using such compounds or compositions to treat respiratory conditions (e.g., asthma or COPD).

Triarylpyridines: A versatile small molecule scaffold for G-quadruplex recognition

The triarylpyridines are potent G-quadruplex ligands that are highly discriminating against duplex DNA and show promising selectivity between intramolecular quadruplexes. The Royal Society of Chemistry.

AMIDOPYRAZOLE DERIVATIVE

A platelet coagulation inhibitor which inhibits neither COX-1 nor COX-2 is provided. The inhibitor is a compound represented by general formula (I): wherein Ar1 and Ar2 independently represent a 5- or 6-membered aromatic heterocyclic group optionally substituted with 1 to 3 substituents, or a phenyl group optionally substituted with 1 to 3 substituents; R1 represents a lower acyl group, carboxyl group, a lower alkoxycarbonyl group, a lower alkoxy group, a lower alkyl group optionally substituted with 1 or 2 substituents, a carbamoyl group optionally substituted with 1 or 2 substituents, an oxamoyl group optionally substituted with 1 or 2 substituents, an amino group optionally substituted with 1 or 2 substituents, a 4- to 7-membered alicyclic heterocyclic group optionally substituted with 1 or 2 substituents, a phenyl group optionally substituted with 1 to 3 substituents, or a 5- or 6-membered aromatic heterocyclic group optionally substituted with 1 to 3 substituents; and R2 represents hydrogen atom, a halogeno group, or the like.