515114-52-0

Basic information

• Product Name: (±)-3-(1-(dimethylamino)-2-methylpentan-3-yl)phenol
• Synonyms: (±)-3-(1-(dimethylamino)-2-methylpentan-3-yl)phenol
• CAS NO: 515114-52-0
• Molecular Weight: 221.343
• Mol File: 515114-52-0.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: (±)-3-(1-(dimethylamino)-2-methylpentan-3-yl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: (±)-3-(1-(dimethylamino)-2-methylpentan-3-yl)phenol(515114-52-0)
• EPA Substance Registry System: (±)-3-(1-(dimethylamino)-2-methylpentan-3-yl)phenol(515114-52-0)

Safety Data

• Hazardous Substances Data: 515114-52-0(Hazardous Substances Data)

Usage

General Description

(±)-3-(1-(dimethylamino)-2-methylpentan-3-yl)phenol, also known as DMPP, is a synthetic chemical compound with a molecular formula of C14H23NO. It is a potent activator of the transient receptor potential cation channel, subfamily A, member 1 (TRPA1) and a transient receptor potential cation channel, subfamily V, member 1 (TRPV1). DMPP has been used in various medicinal and pharmaceutical applications due to its ability to modulate these ion channels, which are involved in the perception of pain, temperature, and inflammation. Additionally, DMPP has been studied for its potential role in controlling the release of neurotransmitters and its potential as a therapeutic target for addressing pain and sensory disorders. However, further research is needed to fully understand the potential benefits and risks associated with the use of DMPP.

Upstream product

• 50-00-0 formaldehyd 
• 1369205-80-0 toluene-4-sulfonic acid 3-propionylphenyl ester 
• 1369205-84-4 toluene-4-sulfonic acid 3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenyl ester 
• 1369205-81-1 toluene-4-sulfonic acid 3-(3-dimethylamino-1-ethyl-1-hydroxy-2-methylpropyl)phenyl ester 
• 1369205-83-3 toluene-4-sulfonic acid 3-[1-(2-dimethylamino-1-methylethyl)propenyl]phenyl ester 
• 1369205-94-6 toluene-4-sulfonic acid 3-(3-dimethylamino-2-methylpropionyl)phenyl ester 
• 1343471-61-3 rac-3-(dimethylamino)-1-(3-hydroxyphenyl)-2-methylpropan-1-one 
• 13103-80-5 1-(3-hydroxyphenyl)propan-1-one 
• 1313429-14-9 2-cyano-3-(3-methoxy-phenyl)-pentanoic acid ethyl ester 
• 1313374-17-2 N,N-dimethyl-2-methyl-3-(3-methoxyphenyl)valeramide 
• 1313429-27-4 3-(3-methoxy-phenyl)-2-methyl-pentanoic acid ethyl ester 
• 1616-70-2 2-methyl-3-(3-methoxyphenyl)valeric acid 
• 1313429-25-2 2-cyano-3-(3-methoxy-phenyl)-2-methyl-pentanoic acid 
• 1313429-24-1 2-methyl-3-(3-methoxyphenyl)pentanenitrile 

Downstream Products

• 175591-09-0 3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol hydrochloride 
• 1243574-48-2 C₂₄H₄₀N₂O₄ 
• 175591-09-0 tapentadol hydrochloride 
• 175591-23-8 tapentadol 
• 1314003-87-6 (rac)-tapentadol-PABA carbamate tert-butyl ester 

Relevant articles and documents

Novel Intermediate Used for Preparing Tapentadol or Analogues Thereof

The invention discloses a novel intermediate for preparing tapentadol and analogues thereof, wherein the structural formula is shown as formula I or II, and the groups are defined as the specification. The invention further discloses a method for preparing the novel intermediate and use of the intermediate for preparing tapentadol and analogues thereof. The invention can remarkably improve the product yield and quality of tapentadol, reduce the production cost, and simplify the production procedure. The preparation process is environment friendly, thus more suitable for the requirements of industrial production.

NOVEL INTERMEDIATE USED FOR PREPARING TAPENTADOL OR ANALOGUES THEREOF

The invention discloses a novel intermediate for preparing tapentadol and analogues thereof, wherein the structural formula is shown as formula I or II, and the groups are defined as the specification. The invention further discloses a method for preparing the novel intermediate and use of the intermediate for preparing tapentadol and analogues thereof. The invention can remarkably improve the product yield and quality of tapentadol, reduce the production cost, and simplify the production procedure. The preparation process is environment friendly, thus more suitable for the requirements of industrial production.

PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE

Provided is a process for the preparing l-phenyl-3-dimethylaminopropane derivatives of formula I, (The formula should be inserted here) and its pharmaceutically acceptable salts thereof via novel intermediates.