51521-95-0 Usage
Description
5-(Aminomethyl)furan-2-carboxylic acid hydrochloride is an organic compound with the chemical formula C5H6NO2·HCl. It is a derivative of furan-2-carboxylic acid, featuring an aminomethyl group attached to the 5-position of the furan ring. 5-(aminomethyl)furan-2-carboxylic acid hydrochloride is known for its reactivity and utility in the synthesis of various organic molecules, particularly those with potential applications in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Industry:
5-(Aminomethyl)furan-2-carboxylic acid hydrochloride is used as a reagent for the preparation of novel heteroaromatic substrates of GABA aminotransferase. GABA aminotransferase is an enzyme that plays a crucial role in the metabolism of neurotransmitters, and its substrates can be used to study the enzyme's function and develop potential therapeutic agents for neurological disorders.
In the synthesis of GABA aminotransferase substrates, 5-(aminomethyl)furan-2-carboxylic acid hydrochloride serves as a key building block, providing a versatile platform for the development of new compounds with potential applications in the treatment of various neurological conditions, such as epilepsy, anxiety, and depression.
Additionally, due to its unique chemical structure, 5-(aminomethyl)furan-2-carboxylic acid hydrochloride may also find applications in other areas of the pharmaceutical industry, such as the development of new drugs targeting different biological pathways or the creation of novel drug delivery systems.
Used in Chemical Industry:
In the chemical industry, 5-(aminomethyl)furan-2-carboxylic acid hydrochloride can be utilized as an intermediate in the synthesis of various organic compounds, including heteroaromatic compounds, which are important building blocks for a wide range of applications, such as agrochemicals, dyes, and materials science.
5-(aminomethyl)furan-2-carboxylic acid hydrochloride's reactivity and functional groups make it a valuable starting material for the development of new synthetic routes and the creation of novel molecules with specific properties. This can lead to the discovery of new compounds with potential applications in various industries, such as the development of new materials with unique properties or the creation of new catalysts for industrial processes.
Check Digit Verification of cas no
The CAS Registry Mumber 51521-95-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,5,2 and 1 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 51521-95:
(7*5)+(6*1)+(5*5)+(4*2)+(3*1)+(2*9)+(1*5)=100
100 % 10 = 0
So 51521-95-0 is a valid CAS Registry Number.
51521-95-0Relevant articles and documents
Furfurylamines from biomass: Transaminase catalysed upgrading of furfurals
Dunbabin, Alice,Subrizi, Fabiana,Ward, John M.,Sheppard, Tom D.,Hailes, Helen C.
, p. 397 - 404 (2017/01/29)
Furfural is recognised as an attractive platform molecule for the production of solvents, plastics, resins and fuel additives. Furfurylamines have many applications as monomers in biopolymer synthesis and for the preparation of pharmacologically active compounds, although preparation via traditional synthetic routes is not straightforward due to by-product formation and sensitivity of the furan ring to reductive conditions. In this work transaminases (TAms) have been investigated as a mild sustainable method for the amination of furfural and derivatives to access furfurylamines. Preliminary screening with a recently reported colorimetric assay highlighted that a range of furfurals were readily accepted by several transaminases and the use of different amine donors was then investigated. Multistep synthetic routes were required to synthesise furfurylamine derivatives for use as analytical standards, highlighting the benefits of using a one step biocatalytic route. To demonstrate the potential of using TAms for the production of furfurals, the amination of selected compounds was then investigated on a preparative scale.
Reactions of alkyl (halomethyl)furancarboxylates with hexamethylenetetramine
Lapina,Pevzner,Potekhin
, p. 1304 - 1309 (2008/02/04)
All isomers of (aminomethyl)furancarboxylic acids were prepared by the Delepine reaction from alkyl (halomethyl)furancarboxylates. Treatment of the initially formed quaternary salt with an ethanolic HCl solution yielded the salts of the corresponding unst
