5153-71-9 Usage
Description
TRANS-4-BROMO-BETA-NITROSTYRENE, also known as trans-p-Bromonitrostyrene, is a halogenated hydrocarbon with a distinctive chemical structure that features a bromine atom and a nitro group attached to a styrene backbone. TRANS-4-BROMO-BETA-NITROSTYRENE is known for its potential applications in various chemical reactions and processes due to its unique properties.
Uses
Used in Chemical Synthesis:
TRANS-4-BROMO-BETA-NITROSTYRENE is used as a Michael acceptor for the organocatalytic asymmetric Michael addition of protected 3-hydroxypropanal to β-nitrostyrenes. This application is significant because it allows for the creation of new compounds with potential applications in various industries, such as pharmaceuticals, materials science, and agrochemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, TRANS-4-BROMO-BETA-NITROSTYRENE is used as a key intermediate in the synthesis of various drug molecules. Its unique chemical structure enables the development of new drugs with improved efficacy and selectivity, contributing to the advancement of medical treatments for various diseases and conditions.
Used in Materials Science:
TRANS-4-BROMO-BETA-NITROSTYRENE is also utilized in the field of materials science for the development of novel materials with specific properties. Its halogenated hydrocarbon nature allows for the creation of materials with enhanced stability, reactivity, or other desirable characteristics, which can be applied in various technological applications.
Used in Agrochemicals:
In the agrochemical industry, TRANS-4-BROMO-BETA-NITROSTYRENE is employed as a building block for the synthesis of new pesticides or other agrochemicals. Its unique structure can be exploited to develop more effective and environmentally friendly products, contributing to sustainable agricultural practices and food security.
Check Digit Verification of cas no
The CAS Registry Mumber 5153-71-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,5 and 3 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 5153-71:
(6*5)+(5*1)+(4*5)+(3*3)+(2*7)+(1*1)=79
79 % 10 = 9
So 5153-71-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H6BrNO2/c9-8-3-1-7(2-4-8)5-6-10(11)12/h1-6H/b6-5+
5153-71-9Relevant articles and documents
Catalytic Asymmetric Construction of Tertiary Carbon Centers Featuring an α-Difluoromethyl Group with CF2H-CH2-NH2as the "building Block"
Gao, Fengyun,Guo, Yifei,Sun, Mengmeng,Wang, Yalan,Yang, Changyan,Wang, Yuqiang,Wang, Kairong,Yan, Wenjin
supporting information, p. 2584 - 2589 (2021/04/13)
We report here for the first time a novel difluoromethylated ketimine building block condensed by thioisatin and difluoroethylamine, offering efficient access to a broad range of enantioenriched products bearing difluoroethylamine units (27 examples, ≤98% yield, >99% ee) in the presence of quinine-derived squaramide. Further transformation of the intermediate would generate a variety of versatile functional blocks like α-difluoromethyl amines, β-amino acid, and β-diamine with retention of the enantiomeric excess at the difluoromethyl-bound carbon.
Metal-free Synthesis of β-Nitrostyrenes via DDQ-Catalyzed Nitration
Min, Sun-Joon,Park, Sangwoon,Yoon, Seungri
, p. 525 - 528 (2021/02/22)
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Geometrically Selective Denitrative Trifluoromethylthiolation of β-Nitrostyrenes with AgSCF3for (E)-Vinyl Trifluoromethyl Thioethers
Fang, Ge,Hong, Jianquan,Huang, Shuai,Jiang, Chao,Liu, Yang,Zhang, Wei,Zheng, Changge
supporting information, (2020/07/03)
An efficient copper(II)-promoted denitrative trifluoromethylthiolation under mild reaction conditions has been developed for vinyl trifluoromethyl thioethers to construct Cvinyl-SCF3 bonds with stable AgSCF3 as a source of the trifluoromethylthio. This reaction system tolerates a broad range of functional groups to commendably achieve a high product yield and excellent stereoselectivity of E/Z.
