51607-79-5

Basic information

• Product Name: 2,5-anhydro-d-sorbitol
• Synonyms: 2,5-anhydro-d-sorbitol
• CAS NO: 51607-79-5
• Molecular Weight: 164.158
• Mol File: 51607-79-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2,5-anhydro-d-sorbitol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-anhydro-d-sorbitol(51607-79-5)
• EPA Substance Registry System: 2,5-anhydro-d-sorbitol(51607-79-5)

Safety Data

• Hazardous Substances Data: 51607-79-5(Hazardous Substances Data)

Upstream product

• 50-70-4 D-sorbitol 
• 23261-20-3 1,2:5,6-dianhydrogalactitol 
• 68774-47-0 2,5-anhydro-1,6-di-O-trityl-DL-altritol 

Relevant articles and documents

Dehydration of sorbitol to isosorbide over H-beta zeolites with high Si/Al ratios

Conversion of sorbitol to isosorbide by heterogeneous catalysts is a challenge in biorefinery. Herein, H-beta zeolites with specific Si/Al ratios uniquely give isosorbide in up to 76% yield under mild conditions. Mechanistic study has suggested that acid sites on hydrophobic internal surface are active for this reaction.

Hydrophilic sulfonic acid-functionalized micro-bead silica for dehydration of sorbitol to isosorbide

Different (3-mercaptopropyl)trimethoxysilane (MPTS) loadings of sulfonic acid-functionalized micro-bead silica (SA-SiO2) were prepared by silylation and oxidation, and characterized by elemental analysis, SEM, FT-IR, TGA, NH3-TPD, BET N2 adsorption-desorption and 13C NMR CP/MAS. The as-prepared SA-SiO2 showed strong hydrophilic nature and excellent catalytic performance for dehydration of sorbitol to isosorbide. The selectivity to isosorbide is obviously affected by the MPTS loading. Using SA-SiO2 as a solid catalyst with 60.5% MPTS loading, 100% sorbitol conversion and 84% yield of isosorbide are achieved at 120 °C for 10 h under vacuum. The catalyst was reused 10 times without noticeable loss of activity and selectivity.

INTEGRATED CONTINUOUS PROCESS FOR ANHYDRO SUGAR ALCOHOL MANUFACTURE

An integrated continuous process is disclosed for the manufacture of high purity, polymer grade dianhydro sugar alcohols, such as isosorbide, by the dehydration of corresponding sugar alcohols. The water vapors evolved during the dehydration are used to separate product dianhydro sugar alcohols from the high boiling byproducts in the reaction mass. The product is recovered from the vapor stream as high purity crystals. The high boiling reaction byproducts are recycled.