51755-56-7

Basic information

• Product Name: Silane, [(3-methoxyphenyl)methyl]trimethyl-
• CAS NO: 51755-56-7
• Molecular Formula: C11H18OSi
• Molecular Weight: 194.349
• Mol File: 51755-56-7.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Silane, [(3-methoxyphenyl)methyl]trimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, [(3-methoxyphenyl)methyl]trimethyl-(51755-56-7)
• EPA Substance Registry System: Silane, [(3-methoxyphenyl)methyl]trimethyl-(51755-56-7)

Safety Data

• Hazardous Substances Data: 51755-56-7(Hazardous Substances Data)

Upstream product

• 766-85-8 3-methoxy-1-iodobenzene 
• 69833-15-4 tris{(trimethylsilyl)methyl}indium 
• 13170-43-9 (trimethylsilyl)methylmagnesium chloride 
• 75-77-4 chloro-trimethyl-silane 
• 2398-37-0 3-methoxyphenyl bromide 
• 1822-00-0 trimethylsilylmethyllithium 
• 2845-89-8 1-chloro-3-methoxy-benzene 
• 824-98-6 m-methoxybenzyl chloride 
• 101079-83-8 2-chloro-5-methoxybenzyl chloride 
• 762-72-1 allyl-trimethyl-silane 
• 13726-18-6 1-chloro-4-chloromethyl-2-methoxybenzene 
• 100-84-5 1-methoxy-3-methyl-benzene 

Downstream Products

• 591-31-1 3-methoxy-benzaldehyde 
• 237763-20-1 1′-(3-methoxyphenyl)-2′-phenylethan-2′-ol 
• 1271631-59-4 2-(3-methoxyphenyl)-1-(pyridin-4-yl)ethanol 
• 1226372-96-8 1-(4-bromophenyl)-2-(3-methoxyphenyl)ethanol 
• 1250895-32-9 1-(3-methoxyphenyl)hexan-2-ol 
• 1644191-25-2 ((3-methoxyphenyl)methylene)bis(trimethylsilane) 
• 82102-27-0 1-methoxy-3-[(1E,3E)-4-phenylbuta-1,3-dien-1-yl]benzene 
• 93340-40-0 2-(3-methoxystyryl)naphthalene 
• 39032-14-9 1-[(E)-2-(4-methoxyphenyl)ethenyl]-3-methoxybenzene 
• 39032-14-9 1-methoxy-3-(4-methoxystyryl)benzene 
• 14064-41-6 (E)-3-methoxystilbene 
• 14168-83-3 (Z)-1-(3-methoxyphenyl)-2-phenylethene 

Relevant articles and documents

para-Selective Benzylation of Aryl Iodides by the in situ Preparation of ArIF2: a Hypervalent Iodine-Guided Electrophilic Substitution

Hypervalent iodine-guided electrophilic substitution (HIGES) was described previously for the para-selective benzylation of aryl-λ3-iodane diacetates. One drawback of the method was the synthesis and isolation of hypervalent iodine starting mat

Murahashi Cross-Coupling at ?78 °C: A One-Pot Procedure for Sequential C?C/C?C, C?C/C?N, and C?C/C?S Cross-Coupling of Bromo-Chloro-Arenes

The coupling of organolithium reagents, including strongly hindered examples, at cryogenic temperatures (as low as ?78 °C) has been achieved with high-reactivity Pd-NHC catalysts. A temperature-dependent chemoselectivity trigger has been developed for the selective coupling of aryl bromides in the presence of chlorides. Building on this, a one-pot, sequential coupling strategy is presented for the rapid construction of advanced building blocks. Importantly, one-shot addition of alkyllithium compounds to Pd cross-coupling reactions has been achieved, eliminating the need for slow addition by syringe pump.

Palladium-catalyzed C(sp 3)-C(sp 2) cross-coupling of (trimethylsilyl)methyllithium with (hetero)aryl halides

The palladium-catalyzed direct cross-coupling of a range of organic chlorides and bromides with the bifunctional C(sp3)-(trimethylsilyl)methyllithium reagent is reported. The use of Pd-PEPPSI-IPent as the catalyst allows for the preparation of structurally diverse and synthetically versatile benzyl- and allylsilanes in high yields under mild conditions (room temperature) with short reaction times.