51770-98-0

Basic information

• Product Name: 2-ethoxyacetamide
• Synonyms: 2-Ethoxyacetamide; acetamide, 2-ethoxy-; Ethoxymethylformamide
• CAS NO: 51770-98-0
• Molecular Formula: C₄H₉NO₂
• Molecular Weight: 103.1198
• Mol File: 51770-98-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 216.2°C at 760 mmHg
• Flash Point: 116.3°C
• Density: 1.013g/cm³
• Vapor Pressure: 0.142mmHg at 25°C
• Refractive Index: 1.422
• CAS DataBase Reference: 2-ethoxyacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethoxyacetamide(51770-98-0)
• EPA Substance Registry System: 2-ethoxyacetamide(51770-98-0)

Safety Data

• Hazardous Substances Data: 51770-98-0(Hazardous Substances Data)

Upstream product

• 14077-58-8 ethoxyacetyl chloride 
• 817-95-8 ethyl 2-ethoxyethanoate 
• 141-52-6 sodium ethanolate 
• 79-07-2 Chloroacetamide 
• 7664-41-7 ammonia 
• 60-29-7 diethyl ether 
• 861524-18-7 2-acetyl-4-ethoxy-3-oxo-butyric acid ethyl ester 
• 627-03-2 3-oxapentanoic acid 
• 623-73-4 diazoacetic acid ethyl ester 
• 62957-60-2 2-ethoxyacetonitrile 

Downstream Products

• 62957-60-2 2-ethoxyacetonitrile 
• 627-03-2 3-oxapentanoic acid 

Relevant articles and documents

Chemoenzymatic Dynamic Kinetic Resolution of Amines in Fully Continuous-Flow Mode

In this study, lipase-mediated dynamic kinetic resolution (DKR) of various benzylic amines (1a-g) is presented which is realized in a so far unprecedented fully continuous-flow system. The DKR process applying sol-gel immobilized lipase B from Candida antarctica as biocatalyst, palladium on 3-aminopropyl-functionalized silica as racemization catalyst, isopropyl 2-ethoxyacetate as acylating agent, ammonium formate as hydrogen and nitrogen sources, and 2-methyl-2-butanol as solvent under regulated pressure provided the desired products in moderate to good yields with excellent enantiomeric excesses.

APELIN RECEPTOR AGONISTS AND METHODS OF USE

The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.

Reaction of Carbenes with Cyclic Ethers in the Presence of Nucleophiles. A Three-Component Coupling Reaction

Ternary reaction systems consisting of a carbene , a cyclic ether (THF, THP) and a protic nucleophile (alcohol, water, carboxylic acid, thiol, or amine) give the corresponding three-component coupling products which are produced via ethereal oxonium ylide intermediates.The mechanism leading to the product formation has been studied in which protonation of carbenes is excluded.