51856-25-8

Basic information

• Product Name: 6H-THIENO[2,3-B]PYRROLE-5-CARBOXYLIC ACID
• Synonyms: 6H-THIENO[2,3-B]PYRROLE-5-CARBOXYLIC ACID
• CAS NO: 51856-25-8
• Molecular Formula: C7H5NO2S
• Molecular Weight: 167.19
• Mol File: 51856-25-8.mol
• Article Data: 7

Chemical Properties

• Melting Point: 207 °C (decomp)
• Boiling Point: 437.4 °C at 760 mmHg
• Flash Point: 218.3 °C
• Appearance: /
• Density: 1.609 g/cm³
• PKA: 4.37±0.30(Predicted)
• CAS DataBase Reference: 6H-THIENO[2,3-B]PYRROLE-5-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 6H-THIENO[2,3-B]PYRROLE-5-CARBOXYLIC ACID(51856-25-8)
• EPA Substance Registry System: 6H-THIENO[2,3-B]PYRROLE-5-CARBOXYLIC ACID(51856-25-8)

Safety Data

• Hazardous Substances Data: 51856-25-8(Hazardous Substances Data)

Usage

General Description

6H-thieno[2,3-b]pyrrole-5-carboxylic acid is a chemical compound with a unique structure that consists of a thieno[2,3-b]pyrrole ring fused to a carboxylic acid group at the 5-position. 6H-Thieno[2,3-b]pyrrole-5-carboxylic acid is a heterocyclic organic molecule that can be used in various organic synthesis reactions and medicinal chemistry research. Its structure and reactivity make it a potential building block for the synthesis of complex organic molecules and pharmaceutical compounds. The carboxylic acid functionality also enables the compound to participate in important chemical reactions such as esterification and amidation, expanding its synthetic utility. Additionally, its potential biological activity makes it an interesting target for drug discovery and development. Overall, 6H-thieno[2,3-b]pyrrole-5-carboxylic acid is a versatile chemical compound with potential applications in both organic synthesis and medicinal chemistry.

Upstream product

• 335030-68-7 ethyl (Z)-2-azido-3-(3-thienyl)prop-2-enoate 
• 498-62-4 3-thiophene carboxaldehyde 
• 41405-96-3 N-(3-formyl-thiophen-2-yl)-acetamide 
• 118465-49-9 methyl 6H-thieno[2,3-b]pyrrole-5-carboxylate 
• 35357-56-3 ethyl thieno<2,3-b>pyrrole-5-carboxylate 

Downstream Products

• 250-79-3 6H-thieno[2,3-b]pyrrole 

Relevant articles and documents

FLUORESCENT COMPOUND AND LABELING AGENT COMPRISING THE SAME

A novel fluorescent compound having a high light fastness, high fluorescence quantum yield and sharp absorption spectrum, which emits fluorescence having a wavelength in long wavelength region, as well as its use as a labeling agent, is disclosed. In Form

The discovery of fused pyrrole carboxylic acids as novel, potent d-amino acid oxidase (DAO) inhibitors

The 'NMDA hypofunction hypothesis of schizophrenia' can be tested in a number of ways. DAO is the enzyme primarily responsible for the metabolism of d-serine, a co-agonist for the NMDA receptor. We identified novel DAO inhibitors, in particular, acid 1, which demonstrated moderate potency for DAO in vitro and ex vivo, and raised plasma d-serine levels after dosing ip to rats. In parallel, analogues were prepared to survey the SARs of 1.

Novel thienopyrrole glycogen phosphorylase inhibitors: Synthesis, in vitro SAR and crystallographic studies

Two series of novel thienopyrrole inhibitors of recombinant human liver glycogen phosphorylase a (GPa) which are effective in reducing glucose output from rat hepatocytes are described. Representative compounds have been shown to bind at the dimer interface site of the rabbit muscle enzyme by X-ray crystallography.