51925-38-3

Basic information

• Product Name: Cyclohexanol, 2-(butylamino)-
• CAS NO: 51925-38-3
• Molecular Formula: C10H21NO
• Molecular Weight: 171.283
• Mol File: 51925-38-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Cyclohexanol, 2-(butylamino)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanol, 2-(butylamino)-(51925-38-3)
• EPA Substance Registry System: Cyclohexanol, 2-(butylamino)-(51925-38-3)

Safety Data

• Hazardous Substances Data: 51925-38-3(Hazardous Substances Data)

Upstream product

• 286-20-4 cyclohexane-1,2-epoxide 
• 109-65-9 1-bromo-butane 
• 38898-70-3 cis-2-amino-cyclohexanol-⁽¹⁾ 
• 931-16-8 (+/-)-trans-2-aminocyclohexanol 
• 51925-38-3 (1SR,2SR)-2-n-butylaminocyclohexanol 
• 123-72-8 butyraldehyde 
• 109-73-9 N-butylamine 

Downstream Products

• 1071658-43-9 (1R)-trans-2-Butylamino-cyclohexanol-⁽¹⁾ 
• 51925-38-3 (1S)-trans-2-Butylamino-cyclohexanol-⁽¹⁾ 
• 87767-81-5 C₁₃H₂₄ClN₃O₃ 
• 87767-88-2 Acetic acid (1R,2R)-2-[butyl-(4,5-dihydro-oxazol-2-yl)-amino]-cyclohexyl ester 
• 87785-46-4 2-(n-butyl-(trans-2-hydroxycyclohexyl)amino)oxazoline 
• 87767-71-3 3-n-butyl-1-(2-chloroethyl)-3-(trans-2-hydroxycyclohexyl)urea 

Relevant articles and documents

Quaternary ammoniums and a cationic sodium complex as supramolecular catalysts in ring-opening of epoxides by amines

Supramolecular ionic organocatalysts and a metal-based catalyst were investigated in the ring-opening of epoxides by amines, without any artifice to enhance conversion (i.e., solvophobic effect, extended reaction time, heating, excess of amine, high catalyst loading). Different β-amino-alcohols were obtained in satisfying conversion (50-80%) in 24 h, under mild conditions.

Highly chemoselective addition of amines to epoxides in water

(Chemical Equation Presented) Aminolysis of a variety of epoxides by aliphatic and aromatic amines in water, in the absence of any catalyst with high yields, is reported. β-Amino alcohols were formed under mild conditions with high selectivity and in excellent yields.

Zirconium sulfophenyl phosphonate as a heterogeneous catalyst in the preparation of β-amino alcohols from epoxides

A convenient method for the ring opening of epoxides by aromatic amines, catalysed by zirconium sulfophenyl phosphonate in solvent-free conditions, is described.