52095-39-3

Basic information

• Product Name: 2-ethenyl-4,5-dimethoxybenzaldehyde
• Synonyms: 2-ethenyl-4,5-dimethoxybenzaldehyde
• CAS NO: 52095-39-3
• Molecular Weight: 192.214
• Mol File: 52095-39-3.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 2-ethenyl-4,5-dimethoxybenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethenyl-4,5-dimethoxybenzaldehyde(52095-39-3)
• EPA Substance Registry System: 2-ethenyl-4,5-dimethoxybenzaldehyde(52095-39-3)

Safety Data

• Hazardous Substances Data: 52095-39-3(Hazardous Substances Data)

Upstream product

• 3382-18-1 6,7-dimethoxy-3,4-dihydro-isoquinoline 
• 77-78-1 dimethyl sulfate 
• 5293-43-6 1-bromo-4,5-dimethoxy-2-vinylbenzene 
• 68-12-2 N,N-dimethyl-formamide 
• 5392-10-9 2-bromo-4,5-dimethoxybenzaldehyde 
• 7486-35-3 tri-n-butyl(vinyl)tin 
• 109126-13-8 (2-formyl-4,5-dimethoxy-phenethyl)-trimethyl-ammonium; iodide 

Downstream Products

• 854872-66-5 4,5-dimethoxy-2-vinylbenzoic acid 
• 104215-89-6 4,5-dimethoxy-2-vinyl-benzyl alcohol 
• 15248-39-2 6,7-dimethoxyisoquinoline 
• 121607-68-9 2-ethenyl-4,5-dimethoxybenzaldoxime O-methyl ether 
• 121607-72-5 2-ethenyl-4,5-dimethoxybenzaldoxime O-benzyl ether 
• 80067-55-6 2-ethyl-4,5-dimethoxy-benzaldehyde 
• 2107-69-9 5,6-dimethoxy-1-indanone 
• 293307-82-1 2-{4,5-Dimethoxy-2-[(R)-1-(4-methoxy-naphthalen-1-ylamino)-ethyl]-phenyl}-ethanol 
• 293307-81-0 [(R)-1-(4,5-Dimethoxy-2-vinyl-phenyl)-ethyl]-(4-methoxy-naphthalen-1-yl)-amine 
• 853996-16-4 2-(4,5-dimethoxy-2-vinylphenyl)cyclobutanone 
• 121607-64-5 2-ethenyl-4,5-dimethoxybenzaldoxime 

Relevant articles and documents

Palladium-Catalyzed Tandem Hydrocarbonylative Lactamization and Cycloaddition Reaction for the Construction of Bridged Polycyclic Lactams

The intramolecular hydroaminocarbonylation of alkenes is a compelling tool to rapidly access lactam, a privileged motif ubiquitous in natural products, pharmaceuticals, and agrochemicals. However, selective carbonylation to bridged polycyclic lactams with a lactam nitrogen at a bridgehead position is less explored. We herein report a modular palladium-catalyzed approach to perform a tandem hydrocarbonylative lactamization/Diels-Alder cycloaddition reaction with 2-vinyl aryl aldimines, alkenes, and CO, which offers convenient access to furnish the bridged polycyclic lactams in high yields with high selectivities.

A metal-free method for the facile synthesis of indanonesviathe intramolecular hydroacylation of 2-vinylbenzaldehyde

A facile method for the synthesis of indanones was developed under metal- and additive-free conditions, whereinl-proline served as an efficient and environmentally benign catalyst. Compared with previously synthesized indanones, synthesis by the transition-metal-catalyzed intramolecular hydroacylation of 2-vinylbenzaldehyde provided a more green synthetic pathway to indanone scaffolds with good to excellent yields. More importantly, it could be used to synthsize the anti-AD drug donepezil.

Carbonylative cycloaddition between two different alkenes enabled by reactive directing groups: Expedited construction of bridged polycyclic skeletons

A novel palladium-catalyzed highly selective hydrocarbonylative cycloaddition reaction with two different alkenes in the presence of CO enabled by a reactive directing-group is developed, which offers efficient and convenient access to lactone-containing bridged polycyclic compounds in high yield with high chemo- and stereoselectivities.