52144-09-9Relevant articles and documents
Silyl Assistance in the Intramolecular Addition of Pyridyl Radicals onto Pyridines and Quinolines
Filace, Fabiana,Sánchez-Murcia, Pedro A.,Sucunza, David,Pérez-Redondo, Adrián,álvarez-Buílla, Julio,Gago, Federico,Burgos, Carolina
, p. 1891 - 1896 (2016)
The first example of a stable acylazinium salt obtained by an intramolecular acylpyridine-centered radical attack on azine nitrogen atoms is reported. Depending on the relative position of the bromo substituent on the attacking aminopyridine ring, it is possible to obtain selectively either the N-attack product or a different C-attack derivative. A rationale for this pathway selectivity was obtained from quantum mechanical calculations.