52328-57-1

Basic information

• Product Name: ethyl α-(Z-phenylhydrazono)benzeneacetate
• Synonyms: ethyl α-(Z-phenylhydrazono)benzeneacetate
• CAS NO: 52328-57-1
• Molecular Weight: 268.315
• Mol File: 52328-57-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: ethyl α-(Z-phenylhydrazono)benzeneacetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl α-(Z-phenylhydrazono)benzeneacetate(52328-57-1)
• EPA Substance Registry System: ethyl α-(Z-phenylhydrazono)benzeneacetate(52328-57-1)

Safety Data

• Hazardous Substances Data: 52328-57-1(Hazardous Substances Data)

Upstream product

• 1603-79-8 phenylglyoxylic acid ethyl ester 
• 100-63-0 phenylhydrazine 
• 996-82-7 sodium diethylmalonate 
• 100-34-5 benzene diazonium chloride 
• 153864-57-4 ethyl α-(E-phenylhydrazono)benzeneacetate 
• 100-52-7 benzaldehyde 
• 588-64-7 benzaldehyde phenylhydrazone 
• 64-17-5 ethanol 
• 5413-05-8 ethyl 2-phenylacetoacetate 

Downstream Products

• 3346-44-9 2,5-diphenyl-1,2-dihydro-[1,2,4]triazol-3-one 
• 728-95-0 phenyl-phenylhydrazono-acetic acid 
• 4430-12-0 (phenylazo)benzaldoxime 
• 52328-62-8 C₁₈H₁₈N₂O₄ 
• 1504-78-5 3-phenylquinoxaline-2(1H)-one 
• 1603-79-8 phenylglyoxylic acid ethyl ester 
• 153864-57-4 ethyl α-(E-phenylhydrazono)benzeneacetate 
• 220437-90-1 5-ethoxycarbonyl-2,5-diphenyl<1,2,4>triazolidine-3-thione 

Relevant articles and documents

An emissive and pH switchable hydrazone-based hydrogel

A serendipitous discovery has led to a new hydrazone-based low molecular weight fluorescent super-hydrogelator. The gelation and emission properties can be switched "ON" and "OFF" using pH, enabling the sensing of biogenic amines emanating from spoiled cod.

Hydrazone Photoswitches for Structural Modulation of Short Peptides

Molecules that undergo light-driven structural transformations constitute the core components in photoswitchable molecular systems and materials. Among various families of photoswitches, photochromic hydrazones have recently emerged as a novel class of photoswitches with superb properties, such as high photochemical conversion, spectral tunability, thermal stability, and fatigue resistance. Hydrazone photoswitches have been adopted in various adaptive materials at different length scales, however, their utilization for modulating biomolecules still has not been explored. Herein, we present new hydrazone switches that can photomodulate the structures of short peptides. Systematic investigation on a set of hydrazone derivatives revealed that installation of the amide group does not significantly alter the photoswitching behaviors. Importantly, a hydrazone switch comprising an upper phenyl ring and a lower quinolinyl ring was effective for structural control of peptides. We anticipate that this work, as a new milestone in the research of hydrazone switches, will open a new avenue for structural and functional control of biomolecules.

Oxidation and rearrangement of 5-substituted 5- ethoxycarbonyl[1,2,4]triazolidine-3-thiones

The reaction of ethyl 2-(phenylhydrazono)alkanoates (1) with potassium thiocyanate in acetic acid affords 5-ethoxycarbonyl-substituted [1,2,4]triazolidine-3-thiones (3). Oxidation (KMnO4) converts 3 into 1- ethoxycarbonyl-2,3-dihydro-1H-[1,2,4]