526-87-4

Basic information

• Product Name: CONDURITOL A
• Synonyms: CONDURITOL A;Conduritol-e;5-Cyclohexene-1α,2β,3β,4α-tetrol;Kondurite;cyclohex-5-ene-1,2,3,4-tetrol;(1R,2S,3R,4S)-Cyclohex-5-ene-1,2,3,4-tetrol;Conduritol A, Kondurite;(1R,2S,3R,4S)-rel-5-Cyclohexene-1,2,3,4-tetrol
• CAS NO: 526-87-4
• Molecular Formula: C₆H₁₀O₄
• Molecular Weight: 146.14
• EINECS: 200-258-5
• Product Categories: All Inhibitors;Glycosidase Inhibitors;Inhibitors
• Mol File: 526-87-4.mol
• Article Data: 30

Chemical Properties

• Melting Point: 142-143
• Boiling Point: 281.9 °C at 760 mmHg
• Flash Point: 141.3 °C
• Appearance: /
• Density: 1.666 g/cm³
• Vapor Pressure: 0.000409mmHg at 25°C
• Refractive Index: 1.693
• Storage Temp.: -20°C Freezer
• Solubility: Methanol (Slightly)
• PKA: 13.32±0.70(Predicted)
• CAS DataBase Reference: CONDURITOL A(CAS DataBase Reference)
• NIST Chemistry Reference: CONDURITOL A(526-87-4)
• EPA Substance Registry System: CONDURITOL A(526-87-4)

Safety Data

• Hazardous Substances Data: 526-87-4(Hazardous Substances Data)

Usage

Description

CONDURITOL A, with the CAS number 526-87-4, is a white crystalline powder that serves as a valuable compound in the realm of organic synthesis. Its unique chemical properties make it a versatile and essential component in various chemical reactions and processes.

Uses

Used in Organic Synthesis:
CONDURITOL A is used as a synthetic building block for the creation of various organic compounds. Its chemical properties allow it to be a key component in the synthesis of complex molecules, contributing to the development of new materials and pharmaceuticals.
Used in Pharmaceutical Industry:
CONDURITOL A is used as an intermediate in the synthesis of pharmaceutical compounds. Its role in creating specific drug molecules makes it an important asset in the development of new medications and therapies.
Used in Chemical Research:
CONDURITOL A is used as a research tool in the field of chemistry. Its unique properties and reactivity make it a valuable compound for studying various chemical reactions and mechanisms, furthering our understanding of organic chemistry and its applications.

InChI:InChI=1/C6H10O4/c7-3-1-2-4(8)6(10)5(3)9/h1-10H

Upstream product

• 120063-28-7 anti-3,5,7,8-tetraoxa-4,4-dimethyl-tricyclo<5.2.2.0^2,6>undec-10-ene 
• 4381-96-8 (+/-)-1,2,3,4-tetra-O-acetylconduritol E 
• 4381-96-8 (+/-)-tetra-O-acetylconduritol F 
• 4381-96-8 (+/-)-(1,3/2,4)-1,2,3,4-tetra-O-acetyl-5-cyclohexene-1,2,3,4-tetrol 
• 17793-95-2 cis-1,2-dihydrocatechol 
• 4381-96-8 (+/-)-tetraacetylconduritol C 
• 17793-95-2 (1RS,2RS)-cyclohexa-3,5-diene-1,2-diol 
• 80177-99-7 (1α,5α,6β,10β)-2,4,7,9-tetraoxa-3,3,8,8-tetramethyltricyclo<8.2.0^1.5.0^6.10>dodec-11-ene 
• 488-73-3 (+)-proto-quercitol 
• 1360452-45-4 C₁₂H₁₈O₄ 
• 1157852-09-9 1,2:3,4-di-O-isopropylidene-5R-(+)-proto-quercitol 
• 129745-62-6 (-)-(4R,5S,6R)-4,5,6-tris(<(tert-butyl)dimethylsilyl>oxy)cyclohex-2-en-1-one 
• 129745-63-7 (-)-1D-2,3,4-tris-O-<(tert-butyl)dimethylsilyl>cyclohex-2-ene-1,2,4/3-tetrol 
• 129829-55-6 (-)-(1R,4R,5R,6R)-5-exo,6-endo-bis(<(tert-butyl)dimethylsilyl>oxy)-7-oxabicyclo<2.2.1>heptan-2-one 

Downstream Products

• 18779-57-2 1,2,3,4,5,6-hexa-O-acetyl-muco-inositol 
• 526-99-8 meso-galactaric acid 
• 20089-18-3 cyclohexanetetrol-(1r,2t,3t,4c) 
• 347377-81-5 (+)-(1S,2R,3R,4S)-1,4-Dibenzoyloxy-5-cyclohexene-2,3-diol 
• 253584-54-2 (+)-(1S,2R,3R,4S)-1,4-Dibenzoyloxy-2,3-di[(2,2,2-trichloroethoxy)carbonyl]oxy-5-cyclohexene 
• 347377-79-1 C₂₈H₂₃NO₆ 
• 347377-76-8 (+)-(1S,2R,3R,4S)-1,4-Dibenzoyloxy-2-(N-benzyl)carbamyl-5-cyclohexene-3-ol 
• 347377-80-4 C₂₈H₂₅NO₈ 
• 347377-82-6 C₂₉H₂₅NO₈ 
• 347377-78-0 C₂₉H₂₄F₃NO₉S 
• 113973-61-8 1,2,3,6-tetra-O-acetyl-muco-inositol 
• 113863-67-5 di-O-acetylconduritol 
• 488-55-1 muco-inositol 

Relevant articles and documents

Concise synthesis of (+)-conduritol F and inositol analogues from naturally available (+)-proto-quercitol and their glucosidase inhibitory activity

An effective synthesis of (+)-conduritol F, (+)-chiro- and (+)-epi-inositols from naturally available (+)- proto-quercitol is described. This synthetic method provides a concise synthesis of cyclitols in enantiomerically pure form. Of the synthesized cyclitols, (+)-conduritol F potently inhibits type I α-glucosidase with an IC50 value of 86.1 lM, which is five times greater than the standard antidiabetic drug, acarbose.

Directed dihydroxylation of cyclic allylic alcohols and trichloroacetamides using OsO4/TMEDA

The oxidation of a range of cyclic allylic alcohols and amides with OsO4/TMEDA is presented. Under these conditions, hydrogen bonding control leads to the (contrasteric) formation of the syn isomer in almost every example that was examined. Evidence for the bidentate binding of TMEDA to OsO4 is presented and a plausible mechanism described.

Catalytic behaviour of chloroperoxidase from Caldariomyces fumago in the oxidation of cyclic conjugated dienes

Chloroperoxidase from Caldariomyces fumago has been investigated as a catalyst for the oxidation of cyclic conjugated dienes. The nature of the substituents and the size of the carbocycle affect the enantioselectivity of the enzyme. An unexpected course o