52601-80-6

Basic information

• Product Name: N,N',N''-TRI-P-TOSYLDIETHYLENETRIAMINE, DISODIUM SALT
• Synonyms: N,N',N''-TRI-P-TOSYLDIETHYLENETRIAMINE, DISODIUM SALT;N,N',N''-TRITOSYLDIETHYLENETRIAMINE DISODIUM SALT;N,N',N"-tri-p-tosyl-3,3'-iminobispropylamine, disodium
• CAS NO: 52601-80-6
• Molecular Formula: C₂₅H₂₉N₃O₆S₃*2Na
• Molecular Weight: 609.69
• Product Categories: Nitrogen Compounds;Organic Building Blocks;Protected Amines
• Mol File: 52601-80-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 275 °C (dec.)(lit.)
• Appearance: /
• Solubility: 95% ethanol: soluble25mg/mL, clear, colorless to yellow
• BRN: 3585044
• CAS DataBase Reference: N,N',N''-TRI-P-TOSYLDIETHYLENETRIAMINE, DISODIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: N,N',N''-TRI-P-TOSYLDIETHYLENETRIAMINE, DISODIUM SALT(52601-80-6)
• EPA Substance Registry System: N,N',N''-TRI-P-TOSYLDIETHYLENETRIAMINE, DISODIUM SALT(52601-80-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 3
• Hazardous Substances Data: 52601-80-6(Hazardous Substances Data)

Usage

Uses

N,N′,N′′-Tritosyldiethylenetriamine disodium salt may be used in the preparation of tritosylate of 1,4,7-triazacyclononane, via reaction with 1,2-dibromoethane in DMF. It may be used in the preparation of 1,4,7-triazacyclononane, via reaction with ditosyl derivative of 1,2-ethanediol.

General Description

N,N′,N′′-Tritosyldiethylenetriamine is a tosyl derivative and its complexation with Ag(I) and Cu(II) is reported.

Upstream product

• 56187-04-3 1,4,7-tritosyl-1,4,7-triazaheptane 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 94530-07-1 1,4,7-tris-(4-tolylsulphonyl)-1,4,7,10-tetraazacyclododecane 
• 52601-74-8 N¹,N⁴,N⁷,N¹⁰,N¹³-pentatosyl-1,4,7,10,13-penta-azacyclopentadecane 
• 78668-28-7 3,6,9-tris-(toluene-4-sulfonyl)-3,6,9,15-tetraaza-bicyclo[9.3.1]pentadeca-1⁽¹⁴⁾,11⁽¹⁵⁾,12-triene 
• 52667-89-7 N,N',N-tris(p-toluenesulfonyl)-1,4,7-triazacyclononane 
• 76102-72-2 6,9,12-tris(p-tolylsulfonyl)-6,9,12-triazaheptadecane-1,17-bis(methanesulfonate) 
• 76102-77-7 6,9,12-tris(p-tolylsulfonyl)-6,9,12-triazaheptadecane-1,17-diol 
• 56187-01-0 1,4,7,13,16,19-hexakis(p-tolylsulfonyl)-1,4,7,13,16,19-hexaazacyclotetracosane 
• 125682-97-5 1,9-bis<<6-<(mesyloxy)methyl>pyridin-2-yl>methyl>-2,5,8-tritosyl-2,5,8-triazanonane 
• 441799-29-7 C₄₅H₄₃N₃O₈S₃ 
• 441799-23-1 C₄₅H₄₃N₃O₈S₃ 
• 441799-27-5 C₄₁H₄₇N₃O₈S₃ 
• 441799-21-9 C₄₁H₄₇N₃O₈S₃ 
• 441799-28-6 C₄₁H₄₃N₃O₈S₃ 
• 441799-22-0 C₄₁H₄₃N₃O₈S₃ 

Relevant articles and documents

METHOD FOR PREPARING NOTA DERIVATIVE

The present invention discloses Method for preparing NOTA derivative. Firstly, take 4-methylsulfonyl chloride and diethylenetriamine in tosyl group reaction to obtain the first product. And, take the first product and sodium methoxide in the first substitution reaction to obtain the second product. Further, take 4-methylsulfonyl chloride and ethylene glycol in tosyl group reaction to obtain a third product. The second product is coupled to the third product to obtain a fourth product. Take the fourth product and sulfuric acid in the second substitution reaction. Finally, a final product is obtained by a bonding reaction with hydrochloric acid. The preparation method improves the water absorption issue of the benzene ring structure compound (TACN) of the NOTA derivative.

Contrast Agents for Magnetic Resonance Imaging

The invention relates to contrast agents for magnetic resonance imaging comprising a chelating ligand and a transition metal ion, said ligand carrying a substituent capable of reacting chemically or biochemically with a target substance while bringing about a change in the spin state.

Improved synthesis and application of lanthanide 1,4,7,10-tetrakis(phosphonomethyl)-1,4,7,10-tetraazacyclododecane complexes Ln(DOTP)

Complexes of lanthanides with 1,4,7,10-tetrakis(phosphonomethyl)-1,4,7,10-tetraazacyclododecane (DOTP) were synthesized for use as shift reagents in a study on the three-dimensional structure of the gene-5 protein encoded by Coli-phage M13.The