52605-77-3

Basic information

• Product Name: Benzenesulfonamide, 4-[(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-ylidene)hydrazino ]-N-2-pyrimidinyl-
• CAS NO: 52605-77-3
• Molecular Formula: C20H17N7O3S
• Molecular Weight: 435.466
• Mol File: 52605-77-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, 4-[(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-ylidene)hydrazino ]-N-2-pyrimidinyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 4-[(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-ylidene)hydrazino ]-N-2-pyrimidinyl-(52605-77-3)
• EPA Substance Registry System: Benzenesulfonamide, 4-[(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-ylidene)hydrazino ]-N-2-pyrimidinyl-(52605-77-3)

Safety Data

• Hazardous Substances Data: 52605-77-3(Hazardous Substances Data)

Upstream product

• 68-35-9 sulfadiazine 
• 89-25-8 edaravone 
• 100-63-0 phenylhydrazine 
• 105-53-3 diethyl malonate 
• 49752-95-6 ethyl 3-oxo-2-(2-{4-[N-(pyrimidin-2-yl)sulfamoyl]phenyl}hydrazono)butanoate 

Downstream Products

• 126517-03-1 4-(5-Chloro-3-methyl-1-phenyl-1H-pyrazol-4-ylazo)-N-pyrimidin-2-yl-benzenesulfonamide 

Relevant articles and documents

Pyrazole and Nicotinonitrile Derivatives Synthesized from Sulfa Drugs, and Their Antibacterial Activity

Utility of sulfadiazine and sulfaguanidine in synthesis of new series of pyrazoles and 2-pyridones is described. Diazotization of sulfadiazine that results in formation of diazonium salt 2 followed by coupling of the latter with active methylene compounds

PART II. APPLICATION TO SOME 1-PHENYL-3-METHYL-4-AZOSULPHONAMIDO-5-PYRAZOLONE DYES

The Vilsmeier-Haak reaction on 3-methylpyrazolone azosulfonamide derivatives (1,2) has been shown to lead to chlorination of the 5-oxopyrazolone system in addition to diformylation of the 3-methyl group to give the corresponding aminoacroleins (3,4) respe