530-56-3

Basic information

• Product Name: 4-HYDROXY-3,5-DIMETHOXYBENZYL ALCOHOL
• Synonyms: LABOTEST-BB LT00053659;FEMA 3137;1,3-DIMETHOXYPYROGALLOL;1,3-DIMETHYLPYROGALLOL;3,5-DIMETHOXY-4-HYDROXYBENZYL ALCOHOL;4-HYDROXY-3,5-DIMETHOXYBENZYL ALCOHOL;PYROGALLOL 1,3-DIMETHYL ETHER;PYROGALLOL DIMETHYL ETHER
• CAS NO: 530-56-3
• Molecular Formula: C₉H₁₂O₄
• Molecular Weight: 184.19
• EINECS: 202-041-1
• Product Categories: Benzhydrols, Benzyl & Special Alcohols
• Mol File: 530-56-3.mol
• Article Data: 14

Chemical Properties

• Melting Point: 50-57 °C(lit.)
• Boiling Point: 261 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.23 g/cm³
• Vapor Pressure: 2.35E-05mmHg at 25°C
• Refractive Index: 1.553
• Solubility: Sparingly soluble (0.40 g/L at 25°C).
• PKA: 9.77±0.23(Predicted)
• BRN: 1873975
• CAS DataBase Reference: 4-HYDROXY-3,5-DIMETHOXYBENZYL ALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDROXY-3,5-DIMETHOXYBENZYL ALCOHOL(530-56-3)
• EPA Substance Registry System: 4-HYDROXY-3,5-DIMETHOXYBENZYL ALCOHOL(530-56-3)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26-36
• RIDADR: UN 2811 6.1/PG 1
• WGK Germany: 3
• RTECS: SL0900000
• Hazardous Substances Data: 530-56-3(Hazardous Substances Data)

Usage

Uses

4-Hydroxy-3,5-dimethoxybenzyl alcohol is a 2,4,6- substituted phenol with antiviral properties.

Definition

ChEBI: A member of the class of phenols that is phenol substituted by a hydroxymethyl group at position 4 and methoxy groups at positions 2 and 6 respectively.

InChI:InChI=1/C9H12O4/c1-12-7-3-6(5-10)4-8(13-2)9(7)11/h3-4,10-11H,5H2,1-2H3

Upstream product

• 50-00-0 formaldehyd 
• 91-10-1 1,3-dimethoxy-2-hydroxy-benzene 
• 6638-05-7 2,6-dimethoxy-4-methylphenol 
• 134-96-3 syringic aldehyde 
• 884-35-5 methyl syringate 
• 39657-47-1 O-acetylsyringic acid chloride 
• 6318-20-3 O-acetylsyringic acid 
• 53669-33-3 4-acetoxy-3,5-dimethoxybenzaldehyde 
• 530-59-6 trans-3,5-dimethoxy-4-hydroxycinnamic acid 
• 7732-18-5 water 
• 116911-85-4 5,5-dimethyl-6-hydroxy-6-(3',5'-dimethoxy-4'-hydroxyphenyl)-1-hexene 
• 75489-75-7 methyl 4-O-(3,5-dimethoxy-4-hydroxybenzyl)-α-D-glucopyranoside 
• 75489-76-8 methyl 6-O-(3,5-dimethoxy-4-hydroxybenzyl)-α-D-glucopyranoside 

Downstream Products

• 3840-31-1 (3,4,5-trimethoxyphenyl)methanol 
• 112468-44-7 4-(3,5-dimethoxy-4-hydroxyphenyl)-1-butene 
• 530-55-2 2,6-dimethoxy-p-quinone 
• 134-96-3 syringic aldehyde 
• 530-57-4 3,5-dimethoxy-4-hydroxybenzoic acid 
• 101788-30-1 bis(3,5-dimethoxy-4-hydroxybenzyl)sulfide 
• 1008144-99-7 C₂₂H₂₉NO₈Si 
• 67-56-1 methanol 
• 33900-62-8 1-(4-Hydroxy-3,5-dimethoxyphenyl)ethanol 
• 693811-18-6 C₁₅H₂₆O₄Si 
• 3840-30-0 5-(chloromethyl)-1,2,3-trimethoxybenzene 
• 111587-60-1 3,5-dinitro-benzoic acid-(3,4,5-trimethoxy-benzyl ester) 
• 7402-30-4 2-(3,4,5-trimethyloxy)benzylmalonic acid diethyl ester 

Relevant articles and documents

Phosphoric acid-modified commercial kieselguhr supported palladium nanoparticles as efficient catalysts for low-temperature hydrodeoxygenation of lignin derivatives in water

Efficient production of high value-added chemicals and biofuels via low-temperature chemoselective HDO of lignin derivatives in water is still a challenge. Here, we construct a low-cost, active and stable Pd/PCE catalyst using phosphoric acid-modified commercial Celite (PCE) as the support, and this catalyst exhibits excellent activity in low-temperature HDO of vanillin as well as other lignin derivatives in water. The superior catalytic performance is due to the presence of P species on the surface of Pd/PCE, accelerating the selective conversion of the intermediate into the final product. Detailed experimental and mechanistic studies reveal that the rapid conversion of the intermediate to the final product proceeds via a free-radical process in an interfacial microenvironment created by intimate interacting between the P species and Pd NPs. The insights of this work provide a new low-cost catalytic system for efficient production of valuable chemicals and future biofuels from lignin derivatives. This journal is

Unusual transformation of 4-hydroxy/methoxybenzylic alcohols via C[sbnd]C ipso-substitution reaction using proton-exchanged montmorillonite as media

We present here proton-exchanged montmorillonite-mediated an unusual transformation of 4-hydroxy and 4-methoxybenzylic alcohols to form symmetrical benzylic ethers and diarylmethanes under mild conditions. Nuclear magnetic resonance spectroscopy and density functional theory calculations support a plausible mechanism, which includes a distinctive aromatic C[sbnd]C ipso-substitution reaction with a hydroxymethyl group as the C-based leaving group.

Thioether type compound as well as synthesis method and application thereof

The invention provides a thioether type compound and also relates to a synthesis method of the thioether type compound and application of the thioether type compound. A chemical structure of the thioether type compound enables the thioether type compound to have a relatively high melting point and be not easily sublimated, so that the thioether type compound has relatively good thermal stability;the thioether type compound has an excellent anti-oxidization capability and has no toxic and side effects, so that the thioether type compound has relatively high utilization safety; secondly, a target compound is synthesized by the synthesis method of the thioether type compound, provided by the invention, by adopting one-step reaction; visibly, the synthesis method is simple to operate, moderate in technological conditions, green and environmentally friendly, and is very suitable for large-scale industrial production. A series of experiments prove that the thioether type compound has an obvious inhibition effect on oxidization of various foods and an anti-oxidization effect of the compound has a certain dose-effect relationship with the concentration of the compound; therefore, the thioether type compound provided by the invention has a wide application prospect and a good market potential.