53117-13-8

Basic information

• Product Name: Methanethione, bis(4-fluorophenyl)-
• CAS NO: 53117-13-8
• Molecular Formula: C13H8F2S
• Molecular Weight: 234.269
• Mol File: 53117-13-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Methanethione, bis(4-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanethione, bis(4-fluorophenyl)-(53117-13-8)
• EPA Substance Registry System: Methanethione, bis(4-fluorophenyl)-(53117-13-8)

Safety Data

• Hazardous Substances Data: 53117-13-8(Hazardous Substances Data)

Upstream product

• 345-92-6 4,4'-Difluorobenzophenone 
• 133528-11-7 triphenylphosphorane 
• 75-15-0 carbon disulfide 
• 462-06-6 fluorobenzene 

Downstream Products

• 435-08-5 1,1,2,2-tetrakis(4-fluoroophenyl)ethylene 
• 102964-61-4 3,3,6,6-tetra(4-flourphenyl)-1,2,4,5-dioxodithiane 
• 345-92-6 4,4'-Difluorobenzophenone 

Relevant articles and documents

Formation of Tetrahydrothiophenes via a Thia-Paternò-Büchi-Initiated Domino Photochemical Reaction

We have established photochemical access to thietane or tetrahydrothiophene compounds from thiobenzophenone derivatives and acrylonitrile, wherein the product selectivity is controlled by a simple adjustment of the reagent concentration in solution. Small libraries of five-membered ring sulfur-containing compounds were prepared through a thia-Paternò-Büchi reaction, followed by a previously unknown regioselective photochemical ring enlargement reaction in a domino process or a stepwise fashion. A mechanism is proposed to rationalize this ring enlargement reaction via a carbene species provided from photoexcited thiocarbonyl compounds.

Stereochemistry of the [4 + 2] cycloaddition of diarylselenoketones with conjugated dienes

The ylides Ph3P=CAr1Ar2 1a-g (Ar = C6H5, p-C6H4Cl, p-C6H4F, m-C6H4CF3, p-C6H4OCH3, p-C6H4-CH3) were treated with elemental selenium (～80°C) to give the corresponding selenoketones Se=CAr1Ar2 2 by Staudinger-chalcogenation. Their reaction with trans,trans-2,4-hexadiene proceeds completely stereospecifically to yield the 2,2-diaryl-3,6-dihydro-cis-3,6-dimethyl-2H-selenapyrans 3. In contrast, the reactions of the selenoketones 2 with cis,trans-2,4-hexadiene proceeds stereoselectively, also giving the dihydro-cis-dimethyl-2H-selenapyrans 3 as the major products, now admixed with small amounts of the dihydro-trans-dimethyl-2H-selenapyran isomers 4. The [4 + 2] cycloaddition of 2 with cis,trans-2,4-hexadiene proceeds stereospecifically, however, when carried out at a pressure of 12 kbar, now yielding 4 as the major products along with the corresponding tetraarylethenes 8. Along with the results of additional mechanistic studies (determination of solvent and substituent effects) it can be concluded that diarylselenoketones are likely to react by means of a concerted [4 + 2] cycloaddition with very reactive conjugated dienes (such as trans,trans-2,4-hexadiene), whereas a stepwise mechanism, resulting in diene cis/trans-isomerization with subsequent mechanistic "leakage" to the concerted pathway, appears to be preferred when a much less reactive conjugated diene such as cis,trans-2,4-hexadiene is employed. The reaction of the corresponding diarylthioketones 5a-g with trans,trans- and cis,trans-2,4-hexadiene, respectively, shows an analogous behavior.