5315-72-0

Basic information

• Product Name: methyl 1-phenyl-1H-1,2,3-triazole-5-carboxylate
• Synonyms: methyl 1-phenyl-1H-1,2,3-triazole-5-carboxylate
• CAS NO: 5315-72-0
• Molecular Weight: 203.2
• Mol File: 5315-72-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: methyl 1-phenyl-1H-1,2,3-triazole-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 1-phenyl-1H-1,2,3-triazole-5-carboxylate(5315-72-0)
• EPA Substance Registry System: methyl 1-phenyl-1H-1,2,3-triazole-5-carboxylate(5315-72-0)

Safety Data

• Hazardous Substances Data: 5315-72-0(Hazardous Substances Data)

Upstream product

• 68418-90-6 β-nitroacrylate de methyle 
• 622-37-7 Phenyl azide 
• 922-67-8 propynoic acid methyl ester 
• 52745-92-3 methyl (E)-3-nitroacrylate 
• 62-53-3 aniline 
• 7377-75-5 methyl 3-phenylamino-2-propenoate 
• 4967-77-5 methyl 1,2,3-triazole-4-carboxylate 
• 71-43-2 benzene 

Downstream Products

• 942-24-5 3-methoxycarbonylindole 
• 1202-04-6 indole-2-carboxylic acid methyl ester 

Relevant articles and documents

Unveiling Potent Photooxidation Behavior of Catalytic Photoreductants

We describe a photocatalytic system that reveals latent photooxidant behavior from one of the most reducing conventional photoredox catalysts, N-phenylphenothiazine (PTH). This aerobic photochemical reaction engages difficult to oxidize feedstocks, such as benzene, in C(sp2)-N coupling reactions through direct oxidation. Mechanistic studies are consistent with activation of PTH via photooxidation and with Lewis acid cocatalysts scavenging inhibitors inextricably formed in this process.

TBAI or KI-Promoted Oxidative Coupling of Enamines and N-Tosylhydrazine: An Unconventional Method toward 1,5- and 1,4,5-Substituted 1,2,3-Triazoles

A novel method for the synthesis of 1,5- and 1,4,5-substituted 1,2,3-triazoles has been reported. This approach is promoted by iodine-TBHP oxidation system using enamines and N-tosylhydrazine as materials, which avoid the dependence of traditional methods on azides and transition metals. Through this approach, various 1,5- and 1,4,5-substituted 1,2,3-triazoles were delivered in moderate to high yields. The mechanistic study indicated that an amino exchange would be involved in the reaction process. Moreover, the product methyl 1-(2-methoxyphenyl)-4-methyl-1H-1,2,3-triazole-5-carboxylate is a useful precursor to anti-influenza A agent, and further application research was conducted. (Figure presented.).

3-nitro- and 3-bromo-3-nitroacrylates in reactions with phenyl azide

1,3-Dipolar cycloaddition of alkyl 3-nitro-and 3-bromo-3-nitroacrylates to phenyl azide gives regioisomeric alkyl 5(4)-nitro-1-phenyl-4,5-dihydro-1H-1,2,3- triazole-4(5)-carboxylates, the corresponding triazoles both with and without nitro group, and alky