53165-22-3

Basic information

• Product Name: Benzenamine, 2-(1,3-dithian-2-yl)-
• CAS NO: 53165-22-3
• Molecular Formula: C10H13NS2
• Molecular Weight: 211.352
• Mol File: 53165-22-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenamine, 2-(1,3-dithian-2-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 2-(1,3-dithian-2-yl)-(53165-22-3)
• EPA Substance Registry System: Benzenamine, 2-(1,3-dithian-2-yl)-(53165-22-3)

Safety Data

• Hazardous Substances Data: 53165-22-3(Hazardous Substances Data)

Upstream product

• 552-89-6 2-nitro-benzaldehyde 
• 35531-58-9 2-(2-nitrophenyl)-1,3-dithiane 
• 505-23-7 1,3 dithiane 
• 622-37-7 Phenyl azide 

Downstream Products

• 1360620-08-1 (E)-3-{[2-(1,3-dithian-2-yl)phenyl]amino}-1-(2,5-dimethyl-1Hpyrrol-1-yl)prop-2-en-1-one 
• 529-23-7 o-aminobenzaldehyde 
• 496043-83-5 2-[2'-(N-Boc-N-trimethylsilyl-amino)phenyl]-1,3-dithiane 
• 496043-95-9 methyl-[2-(2-oxo-2-phenyl-ethyl)-phenyl]-carbamic acid tert-butyl ester 
• 496043-67-5 2-[2'-(N-benzyl-N-Boc-amino)phenyl]-1,3-dithiane 
• 496043-69-7 2-[2'-(N-tert-butyloxycarbonyl-N-prenylamino)phenyl]-1,3-dithiane 
• 396094-76-1 1-[2'-(N-Boc-N-methylamino)phenyl]-4-phenylbutan-2-one 
• 396094-74-9 2-[2'-(N-Boc-N-methylamino)phenyl]-1,3-dithiane 
• 138343-89-2 tert-butyl 2-phenyl-1H-indole-1-carboxylate 
• 98598-96-0 tert-butyl 2-methyl-1H-indole-1-carboxylate 
• 27884-09-9 2-(4-methoxyphenyl)benzo[b]thiophene 
• 3558-24-5 1-methyl-2-phenyl-1H-indole 
• 28540-48-9 2-(2'-phenylethyl)benzo[b]thiophene 
• 765292-75-9 2-[2'-(tert-butyldimethylsilylsulfanyl)phenyl]-1.3-dithiane 

Relevant articles and documents

Palladium-catalyzed intramolecular aryl amination reaction: An expeditious approach to the synthesis of chiral benzodiazocine derivatives

A palladium-catalyzed method for intramolecular amination of aryl bromides and iodides has been developed employing different bulky biaryl phosphanes as ligands and toluene as solvent. A variety of electron-rich aryl halide substrates have been aminated b

Synthesis of 2-substituted benzofurans and indoles using functionalized titanium benzylidene reagents on solid phase

Titanium(IV) benzylidenes bearing a masked oxygen or nitrogen nucleophile in the ortho position were generated from thioacetals, using low-valent titanocene complex, Cp2Ti[P(OEt)3]2. Methylene acetal, alkyl ether, silyl ether, fluoro, tertiary amino, and N-alkyl, N-benzyl, N-prenyl, and N-silyl tert-butyl carbamate groups were tolerated in the titanium alkylidene reagents (Schrock carbenes). Aryl-chlorine bonds were stable to the titanium benzylidene functionality, but there was poor chemoselectivity for the reduction of the thioacetal in the presence of an aryl chloride. The titanium benzylidenes converted Merrifield and Wang resin-bound esters into enol ethers. The oxygen nucleophile was masked as a TMS ether, and when the resin-bound enol ethers bearing this ortho substituent were treated with 1% TFA in dichloromethane, benzofurans were released from resin in high yields. The chameleon catch strategy ensured excellent purity. In a similar way, N-alkylated and N-silylated tert-butyl carbamates were used for the synthesis of N-alkyl and N-Boc indoles, respectively. These traceless solid-phase syntheses of heterocycles are believed to involve post-cleavage modification rather than cyclative termination.

Thermal Reaction of Phenylnitrene with Sulfides

Thermolysis of phenyl azide in the presence of sulfides bearing α-hydrogen atoms leads to the formation of significant amounts of 2-substituted anilines, presumably by Sommelet-Hauser type rearrangement of the intermediate N-phenylsulfimides.