53616-28-7

Basic information

• Product Name: 3H-Pyrazol-3-one, 5-(bromomethyl)-1,2-dihydro-1-methyl-4-(1-methylethyl)-2-phenyl-
• CAS NO: 53616-28-7
• Molecular Formula: C14H17BrN2O
• Molecular Weight: 309.206
• Mol File: 53616-28-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3H-Pyrazol-3-one, 5-(bromomethyl)-1,2-dihydro-1-methyl-4-(1-methylethyl)-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3H-Pyrazol-3-one, 5-(bromomethyl)-1,2-dihydro-1-methyl-4-(1-methylethyl)-2-phenyl-(53616-28-7)
• EPA Substance Registry System: 3H-Pyrazol-3-one, 5-(bromomethyl)-1,2-dihydro-1-methyl-4-(1-methylethyl)-2-phenyl-(53616-28-7)

Safety Data

• Hazardous Substances Data: 53616-28-7(Hazardous Substances Data)

Upstream product

• 479-92-5 propyphenazone 

Downstream Products

• 88913-10-4 3-(N-Hydroxy-N-methylaminomethyl)-4-isopropyl-2-methyl-1-phenyl-3-pyrazolin-5-on 
• 74512-62-2 Acetic acid 2-[(4-isopropyl-2-methyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-ylmethyl)-carbamoyl]-phenyl ester 
• 74512-63-3 2-Hydroxy-N-(4-isopropyl-2-methyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-ylmethyl)-benzamide 
• 74512-64-4 1-phenyl-2-methyl-3-aminomethyl-4-isopropylpyrazolone 
• 525602-01-1 3-[(hydroxyacetamido)methyl]-4-isopropyl-2-methyl-1-phenyl-3-pyrazolin-5-one 
• 525602-00-0 glycinyl-3-hydroxymethylpropyphenazone 
• 83957-94-2 4-Isopropyl-2-methyl-3-(N-methyl-aminomethyl)-1-phenyl-3-pyrazolin-5-on 
• 83957-89-5 5-(hydroxymethyl)-4-isopropyl-1-methyl-2-phenyl-1H-pyrazol-3(2H)-one 
• 61672-58-0 5-Chloromethyl-4-isopropyl-1-methyl-2-phenyl-1,2-dihydro-pyrazol-3-one 

Relevant articles and documents

Biological and metabolic study of naproxen-propyphenazone mutual prodrug

Naproxen-propyphenazone (NAP-PP) esters were synthesized as prodrugs with the aim of improving the therapeutic index through prevention of gastrointestinal irritation and bleeding. The structures of the synthesized NAP-PP hybrid esters were confirmed by I

Synthesis, characterization, in vitro hydrolysis and pharmacodynamic profiles of potential novel mutual prodrugs of N-(2,3-xylyl anthranilic acid)

In present research work, we report the synthesis, in vitro hydrolysis study and pharmacological evaluation of new mutual prodrugs of mefenamic acid (MA) and 1,2 dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenylpyrazol-3-one with the aim of improving the th