53693-57-5Relevant articles and documents
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Mukaiyama,Hoshino
, p. 1946 (1956)
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Synthesis of unsymmetrical phenylurea derivatives via oxidative cross coupling of aryl formamides with amines under metal-free conditions
Reddy, Nagireddy Veera,Kumar, Pailla Santhosh,Reddy, Peddi Sudhir,Kantam, Mannepalli Lakshmi,Reddy, Kallu Rajender
, p. 805 - 809 (2015/02/19)
A new synthetic approach for phenylurea derivatives involving the cross coupling of N-aryl formamides with amines through the formation of isocyanate intermediates in the presence of hypervalent iodine reagents is described.
An efficient and mild protocol for the synthesis of unsymmetrical ureas in the absence of catalyst and additives
Hosseinzadeh, Rahman,Sarrafi, Yaghoub,Aghili, Nora
experimental part, p. 1171 - 1174 (2011/10/04)
A new practical method for the synthesis of unsymmetrical ureas was achieved by reaction of phenylurea with primary and secondary amines under neutral and mild condition in very good yields. The reaction took place in refluxing dioxane and does not require any catalyst or additives.