53720-10-8Relevant articles and documents
Chemo-biological preparation of the chiral building block (R)-4-acetoxy-2-methyl-1-butanol using Pseudomonas putida
Kim, Youngju,Watanabe, Hidenori,Kim, Bieong-Kil,Seu, Young-Bae
experimental part, p. 1658 - 1661 (2012/01/13)
In order to develop new methyl substituted chiral building blocks which are useful for the synthesis of methyl branched natural products, the enantioselective bioreduction of an exo-methylene to a methyl group was investigated. 4-Acetoxy-2-methylene-1-butanol 3 was prepared from itaconic acid over four steps and converted to the chiral alcohol (R)-4-acetoxy-2-methyl-1- butanol 4, by growing cells of Pseudomonas putida. The bioconversion achieved a high enantioselectivity (92% ee) and a high chemical yield (65%) within a relatively short reaction time (18-20 h). Copyright
Synthesis and Radical Polymerization of Itaconates Containing an Adamantyl Ester Group
Matsumoto, Akikazu,Watanabe, Hiroyuki,Otsu, Takayuki
, p. 846 - 852 (2007/10/02)
Itaconates containing a 1-adamantyl or a 3,5-dimethyl-1-adamantyl ester group were prepared and polymerized in the presence of a radical initiator.The polymerization reactivity has been investigated in relation to the structure of ester alkyl groups of the monomer.It has been clarified that the adamantyl-containing polyitaconates show high thermal stability, i.e., high glass transition temperatures and decomposition temperatures.The relationship between polymer structures and thermal properties of polymers from some α- and β-substituted acrylic esters, i.e., acrylates, methacrylates, crotonates, fumarates, and itaconates was discussed .
