53839-05-7

Basic information

• Product Name: o-anisylphosphonic dichloride
• Synonyms: o-anisylphosphonic dichloride
• CAS NO: 53839-05-7
• Molecular Weight: 225.011
• Mol File: 53839-05-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: o-anisylphosphonic dichloride(CAS DataBase Reference)
• NIST Chemistry Reference: o-anisylphosphonic dichloride(53839-05-7)
• EPA Substance Registry System: o-anisylphosphonic dichloride(53839-05-7)

Safety Data

• Hazardous Substances Data: 53839-05-7(Hazardous Substances Data)

Upstream product

• 108-95-2 phenol 
• 69646-14-6 (2-hydroxy-phenyl)-phosphonic acid diethyl ester 
• 2510-86-3 O,O-diethyl O-phenyl phosphate 
• 578-57-4 2-bromoanisole 
• 15286-17-6 diethyl [2-(methoxy)phenyl]phosphonate 

Relevant articles and documents

Enantioselective and Regioselective Hydroetherification of Alkynes by Gold-Catalyzed Desymmetrization of Prochiral Phenols with P-Stereogenic Centers

The gold(I)-catalyzed enantioselective hydroetherification of alkynes was achieved via desymmetrization of prochiral bisphenols bearing P-stereogenic centers. (S)-DTBM-Segphos(AuCl)2/AgNTf2 proved to be a highly efficient catalyst system for this transformation, affording P-chiral cyclic phosphine oxides in good yields with high enantioselectivities (with up to 99% ee). The same catalyst system allowed for the enantioselective desymmetrization of dialkynes. Synthetic transformations of the cyclization products afforded other P-chiral molecules with high enantiospecificity.