53899-17-5 Usage
Description
8-METHOXY-1,2,3,4-TETRAHYDROQUINOLINE is an organic compound with a quinoline structure, featuring a methoxy group at the 8th position and a fully saturated tetrahydro ring. It is known for its potential applications in various chemical and pharmaceutical processes due to its unique molecular structure and reactivity.
Uses
Used in Chemical Synthesis:
8-METHOXY-1,2,3,4-TETRAHYDROQUINOLINE is used as a reactant in the catalytic aerobic dehydrogenation of nitrogen heterocycles. This application takes advantage of its reactivity and ability to participate in chemical reactions, leading to the formation of new compounds with potential uses in various industries.
Used in Pharmaceutical Industry:
8-METHOXY-1,2,3,4-TETRAHYDROQUINOLINE may also be used as a building block or intermediate in the synthesis of various pharmaceutical compounds. Its unique structure can be further modified or functionalized to create new drugs with specific therapeutic properties.
Used in Research and Development:
In the field of research and development, 8-METHOXY-1,2,3,4-TETRAHYDROQUINOLINE can be employed as a starting material or a probe in the investigation of new chemical reactions, mechanisms, and the development of novel synthetic methods. Its reactivity and structural features make it a valuable tool for advancing scientific knowledge and discovering new applications.
Check Digit Verification of cas no
The CAS Registry Mumber 53899-17-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,8,9 and 9 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 53899-17:
(7*5)+(6*3)+(5*8)+(4*9)+(3*9)+(2*1)+(1*7)=165
165 % 10 = 5
So 53899-17-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H13NO/c1-12-9-6-2-4-8-5-3-7-11-10(8)9/h2,4,6,11H,3,5,7H2,1H3
53899-17-5Relevant articles and documents
Selectivity in the Hydrogenation of 6- and 8-Substituted-quinolines
Hoenel, Michael,Vierhapper, Friedrich W.
, p. 1933 - 1939 (2007/10/02)
Quinoline (1) and the 6- or 8-substituted-quinolines (2)-(14) (R = Me, Pri, But, Ph, OMe, OH, CF3, or F) were hydrogenated catalytically on platinum under either weakly basic (solvent MeOH) or strongly acidic (solvent CF3CO2H) conditions.In methanol the only product was the corresponding 1,2,3,4-tetrahydro-compound.In trifluoroacetic acid, compounds hydrogenated in the benzene ring were isolated as major products; both electron-withdrawing and electron-donating substituents at C-6 or C-8 cause (sometimes drastic) reduction in yield.The products were characterized by their 1H and 13C n.m.r. spectra.