5434-50-4

Basic information

• Product Name: 2-(6-bromobenzo[1,3]dioxol-5-yl)acetonitrile
• Synonyms: 2-(6-bromobenzo[1,3]dioxol-5-yl)acetonitrile
• CAS NO: 5434-50-4
• Molecular Formula: C₉H₆BrNO₂
• Molecular Weight: 240.05
• Mol File: 5434-50-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 351.7°Cat760mmHg
• Flash Point: 166.5°C
• Appearance: /
• Density: 1.678g/cm³
• Vapor Pressure: 4.03E-05mmHg at 25°C
• Refractive Index: 1.609
• CAS DataBase Reference: 2-(6-bromobenzo[1,3]dioxol-5-yl)acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(6-bromobenzo[1,3]dioxol-5-yl)acetonitrile(5434-50-4)
• EPA Substance Registry System: 2-(6-bromobenzo[1,3]dioxol-5-yl)acetonitrile(5434-50-4)

Safety Data

• Hazardous Substances Data: 5434-50-4(Hazardous Substances Data)

Usage

General Description

2-(6-bromobenzo[1,3]dioxol-5-yl)acetonitrile is a chemical compound with the molecular formula C9H6BrNO3. It is a pale yellow crystalline solid that is commonly used in organic synthesis and pharmaceutical research. The compound contains a benzodioxole ring with a bromine substituent at the 6-position, and an acetonitrile group attached to the 2-position. It is known for its potential applications in the development of pharmaceutical drugs and agrochemicals. The compound's structure and properties make it a valuable building block for the synthesis of various bioactive molecules and organic compounds. Additionally, it may also possess biological activities and potential therapeutic effects, which makes it an important target for further research and development.

InChI:InChI=1/C9H6BrNO2/c10-7-4-9-8(12-5-13-9)3-6(7)1-2-11/h3-4H,1,5H2

Upstream product

• 64603-67-4 5-bromo-6-(chloromethyl)benzo[d][1,3]dioxole 
• 151-50-8 potassium cyanide 
• 5470-14-4 (6-bromobenzo[1,3]dioxol-5-yl)acetic acid 
• 51665-84-0 methyl (6-bromobenzo<1,3>dioxol-5-yl)acetate 
• 956084-13-2 (6-bromo-benzo[1,3]dioxol-5-yl)-pyruvic acid 
• 4439-02-5 3,4-methylenedioxyphenylacetonitrile 
• 773837-37-9 sodium cyanide 
• 5434-47-9 5-bromo-6-bromomethylbenzo[1,3]dioxole 
• 5025-53-6 5-bromo-6-methylbenzo[d][1,3]dioxole 
• 15930-53-7 6-bromo-3,4-methylenedioxybenzaldehyde 
• 6642-34-8 6-bromopiperonyl alcohol 
• 857794-75-3 2-(6-bromobenzo[1,3]dioxol-5-yl)acetamide 

Downstream Products

• 1365565-34-9 (9H-fluoren-9-yl)methyl 2-(3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)propyl)-4,5-dihydroxyphenethylcarbamate 
• 1174642-41-1 3-cyano-5, 6-methylenedioxy-2-(phenylamino)benzo[b]thiophene 
• 1315506-60-5 (6S,7R,8S)-7-phenyl-6-propyl-5-tosyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]quinoline-8-carbonitrile 
• 1315506-47-8 5-tosyl-5a,6,7,8,8a,9-hexahydro-5H-cyclopenta[b][1,3]dioxolo[4,5-g]quinoline-9-carbonitile 
• 1315506-41-2 N-(2-((6-bromobenzo[d][1,3]dioxol-5-yl)(cyano)methyl)cyclopentyl)-4-methylbenzenesulfonamide 
• 1315506-51-4 N-((2R,3S)-3-(6-bromobenzo[d][1,3]dioxol-5-yl)-3-cyano-2-phenylpropyl)-4-methylbenzenesulfonamide 

Relevant articles and documents

Construction of 2-Arylbenzo[4,5]thieno[2,3-d]thiazole Skeleton via CuCl/S-Mediated Three-Component Reaction

An exclusive thiophene-fused polycyclic I-conjugated 2-arylbenzo[4,5]thieno[2,3-d]thiazole skeleton was constructed via a one-pot CuCl-mediated three-component reaction, using 2-(2-bromophenyl)acetonitrile and aromatic aldehydes as substrates and elementa

Copper-catalyzed domino coupling reaction: An efficient method to synthesize oxindoles

An efficient and novel procedure for a copper catalyzed domino coupling reaction has been developed, which afforded various oxindoles in good to excellent yields with tolerance of various substituents. In addition, this method could be applied to synthesize horsfiline and coerulescine in few steps with high total yields. The Royal Society of Chemistry 2012.

Synthesis of N-alkoxyindol-2-ones by copper-catalyzed intramolecular N-arylation of hydroxamates

The first example of copper-catalyzed intramolecular N-arylation of hydroxamic acid derivatives is presented. Based on this transformation a new method for the synthesis of N-alkoxyindol-2-ones from 2-(2-bromoaryl) acetylhydroxamates has been developed. T