5443-79-8

Basic information

• Product Name: 3-nitro-2-phenylquinoline
• CAS NO: 5443-79-8
• Molecular Formula: C₁₅H₁₀N₂O₂
• Molecular Weight: 250.2521
• Mol File: 5443-79-8.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 409.1°C at 760 mmHg
• Flash Point: 201.2°C
• Density: 1.29g/cm³
• Vapor Pressure: 1.58E-06mmHg at 25°C
• Refractive Index: 1.68
• CAS DataBase Reference: 3-nitro-2-phenylquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-nitro-2-phenylquinoline(5443-79-8)
• EPA Substance Registry System: 3-nitro-2-phenylquinoline(5443-79-8)

Safety Data

• Hazardous Substances Data: 5443-79-8(Hazardous Substances Data)

Upstream product

• 5153-67-3 nitrostyrene 
• 271-58-9 anthranil 
• 529-23-7 o-aminobenzaldehyde 
• 1622312-65-5 3-fluoro-3-nitro-2-phenyl-3,4-dihydroquinoline 
• 614-21-1 2-nitroacetophenone 
• 102-96-5 (2-nitroethenyl)benzene 
• 16714-25-3 2-azidobenzaldehyde 
• 552-89-6 2-nitro-benzaldehyde 
• 78105-37-0 2-chloro-3-nitroquinoline 
• 98-80-6 phenylboronic acid 

Downstream Products

• 36710-53-9 2-phenyl-quinolin-3-ylamine 
• 109130-61-2 10-benzyl-10H-indolo[3,2-b]quinoline 
• 1622312-65-5 3-fluoro-3-nitro-2-phenyl-3,4-dihydroquinoline 
• 1643786-42-8 2-((2R,3R)-2-phenyl-1,2,3,4-tetrahydroquinolin-3-yl)isoindoline-1,3-dione 
• 1620395-12-1 2-((S,3S)-2-phenyl-1,2,3,4-tetrahydroquinolin-3-yl)isoindoline-1,3-dione 
• 102594-89-8 2-(2-phenylquinolin-3-yl)isoindoline-1,3-dione 
• 1607449-13-7 C₂₂H₂₁⁽²⁾HN₂O₂S 
• 1607449-12-6 (2S,3S)-2-phenyl-1,2,3,4-tetrahydroquinolin-3-amine 
• 1607448-82-7 4-methyl-N-(2-phenylquinolin-3-yl)benzenesulfonamide 

Relevant articles and documents

Copper Catalyzed Synthesis of 3-Nitro-Quinolines from Nitro-Olefins and Anthranils: Its Application in the Synthesis of Quindoline

Copper-catalyzed routes have been achieved for the synthesis of 3-nitroquinolines from readily available nitroolefins and anthranils. This reaction proceeds via the [4+2] cycloaddition between anthranils and nitro-styrenes under mild reaction conditions to obtain biologically important heterocycles. A wide range of diversely substituted nitro-olefins and anthranils are successfully employed in this reaction to access a series of 3-nitro-quinolines in 81–93% yields. The synthetic utility of the present methodology is also illustrated in this manuscript. (Figure presented.).