54656-63-2

Basic information

• Product Name: Propanoic acid, 2-methoxy-, methyl ester, (2R)-
• Synonyms: methyl [2(R)-methoxy]propionate;d(+)-O-Methyl-milchsaeure-methylester;(-)-α-Methoxy-propionsaeure-methylester;linksdrehender α-Methoxy-propionsaeure-methylester;d(+)-α-Methoxy-propionsaeure-methylester
• CAS NO: 54656-63-2
• Molecular Formula: C5H10O3
• Molecular Weight: 118.13100
• Mol File: 54656-63-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 136.2±13.0 °C(Predicted)
• Density: 0.973±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Propanoic acid, 2-methoxy-, methyl ester, (2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2-methoxy-, methyl ester, (2R)-(54656-63-2)
• EPA Substance Registry System: Propanoic acid, 2-methoxy-, methyl ester, (2R)-(54656-63-2)

Safety Data

• Hazardous Substances Data: 54656-63-2(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 61915-18-2 R-(+)-2-methoxypropionic acid chloride 
• 547-64-8 methyl lactate 
• 20047-41-0 methyl (2S)-2-bromopropanoate 
• 124-41-4 sodium methylate 
• 17392-83-5 (R)-Methyl lactate 
• 74-88-4 methyl iodide 

Downstream Products

• 887029-63-2 (2R)-2-methoxypropanehydrazide 
• 23943-96-6 (R)-(+)-2-methoxypropionic acid 

Relevant articles and documents

Synthesis of a Tridecasaccharide Lipooligosaccharide Antigen from the Opportunistic Pathogen Mycobacterium kansasii

The outer surfaces of mycobacteria, including the organism that causes tuberculosis, are decorated with an array of immunomodulatory glycans. Among these are lipooligosaccharides (LOSs), a class of molecules for which the function remains poorly understoo

METHODS OF TREATING PULMONARY DISEASES AND DISORDERS

The present disclosure features disclosed method of treating disorders such as COPD, bronchitis and/or asthma using disclosed compounds, optionally together with one or more additional active agents. Contemplated methods include administrating orally or by inhalation to a patient one or more disclosed compounds.

Enantioselective syntheses of α-amino-β-hydroxy acids, [15N]-L-allothreonine and [15N]-L-threonine

The enantioselective synthesis of [15N]-L-allothreonine from ethyl (S)-lactate via methyl (S)-3-methoxymethoxy-2-oxobutanoate 15 is described. The stereogenic centre at C-2 was established by a one-pot, dual enzyme catalysed hydrolysis of the ester (by a lipase) and reductive amination of the ketone of 15 (with leucine dehydrogenase) to give, after deprotection, [15N]-(2S,3S)-2-amino-3-hydroxybutanoic acid as a single diastereomer in 93% yield. [15N]-L-Threonine was prepared by an analogous strategy from methyl (R)-lactate using phenylalanine dehydrogenase in the reductive amination step. This approach may be simply adapted for the incorporation of deuterium and carbon-13.