54879-35-5

Basic information

• Product Name: Benzenesulfonamide, N-(2,2-dimethoxyethyl)-N-[(4-methoxyphenyl)methyl]-4-methyl-
• CAS NO: 54879-35-5
• Molecular Formula: C19H25NO5S
• Molecular Weight: 379.477
• Mol File: 54879-35-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, N-(2,2-dimethoxyethyl)-N-[(4-methoxyphenyl)methyl]-4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N-(2,2-dimethoxyethyl)-N-[(4-methoxyphenyl)methyl]-4-methyl-(54879-35-5)
• EPA Substance Registry System: Benzenesulfonamide, N-(2,2-dimethoxyethyl)-N-[(4-methoxyphenyl)methyl]-4-methyl-(54879-35-5)

Safety Data

• Hazardous Substances Data: 54879-35-5(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 54879-77-5 N-(4-methoxybenzyl)aminoacetaldehyde dimethyl acetal 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 54879-64-0 N-[(4-methoxyphenyl)methyl]-4-methylbenzenesulfonamide 

Relevant articles and documents

Synthesis of tetrahydroisoquinolines through TiCl4-mediated cyclization and Et3SiH reduction

A versatile and efficient telescoped reaction sequence for the synthesis of tetrahydroisoquinolines (THIQs) is reported that uses TiCl4 to promote cyclization of a benzylaminoacetal derivative and Et3SiH for reduction of the intermediate 4-hydroxy-THIQ. This method is complimentary to the classical Pomeranz-Fritsch and related reactions since it tolerates electron-withdrawing substituents and allows access to 8-substituted THIQs.