55441-70-8

Basic information

• Product Name: 6-AMINO-1-METHYL-5-(METHYLAMINO)URACIL
• Synonyms: 6-Amino-2,4-dihydroxy-1-methyl-5-methylaminopyrimidine;6-AMino-1-Methyl-5-(MethylaMino)-2,4(1H,3H)-pyriMidinedione
• CAS NO: 55441-70-8
• Molecular Formula: C₆H₁₀N₄O₂
• Molecular Weight: 170.17
• Product Categories: Nucleotides and Nucleosides;Bases & Related Reagents;Nucleotides;Heterocycles
• Mol File: 55441-70-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: >300°C
• Appearance: white solid
• Density: 1.38 g/cm³
• Refractive Index: 1.605
• Storage Temp.: 2-8°C
• PKA: 9.37±0.40(Predicted)
• Stability: Store Tightly Sealed at RT
• CAS DataBase Reference: 6-AMINO-1-METHYL-5-(METHYLAMINO)URACIL(CAS DataBase Reference)
• NIST Chemistry Reference: 6-AMINO-1-METHYL-5-(METHYLAMINO)URACIL(55441-70-8)
• EPA Substance Registry System: 6-AMINO-1-METHYL-5-(METHYLAMINO)URACIL(55441-70-8)

Safety Data

• Hazardous Substances Data: 55441-70-8(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

InChI:InChI=1/C6H10N4O2/c1-8-3-4(7)10(2)6(12)9-5(3)11/h8H,7H2,1-2H3,(H,9,11,12)

Upstream product

• 14094-37-2 6-amino-5-bromo-1-methylpyrimidine-2,4(1H,3H)-dione 
• 74-89-5 methylamine 
• 2434-53-9 6-amino-1-methyluracil 

Downstream Products

• 199680-96-1 1N-(6-amino-1-methyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-1N-methyl-3-phenyl-(E)-2-propenamide 
• 6050-42-6 3,7,8-trimethyl-3,7-dihydro-purine-2,6-dione 
• 6439-88-9 1,3,7-trimethyl-8-phenylxanthine 
• 453591-34-9 6-((S)-1-Hydroxymethyl-propylamino)-3,7-dimethyl-8-((E)-styryl)-3,7-dihydro-purin-2-one 
• 453591-33-8 6-((R)-1-Hydroxymethyl-propylamino)-3,7-dimethyl-8-((E)-styryl)-3,7-dihydro-purin-2-one 
• 453591-29-2 6-((S)-1-Hydroxymethyl-propylamino)-3,7-dimethyl-8-phenyl-3,7-dihydro-purin-2-one 
• 453591-28-1 6-((R)-1-Hydroxymethyl-propylamino)-3,7-dimethyl-8-phenyl-3,7-dihydro-purin-2-one 
• 453591-27-0 6-(1-hydroxymethyl-propylamino)-3,7-dimethyl-8-phenyl-3,7-dihydro-purin-2-one 
• 453591-26-9 6-(2-hydroxy-ethylamino)-3,7-dimethyl-8-phenyl-3,7-dihydro-purin-2-one 
• 453591-14-5 3,7-Dimethyl-6-methylsulfanyl-8-((E)-styryl)-3,7-dihydro-purin-2-one 
• 453591-10-1 3,7-Dimethyl-8-((E)-styryl)-6-thioxo-1,3,6,7-tetrahydro-purin-2-one 
• 453591-89-4 3,7-dimethyl-8-phenyl-6-thioxo-1,3,6,7-tetrahydro-purin-2-one 
• 199680-97-2 3,7-dimethyl-8-styrylxanthine 
• 155588-82-2 3,7-Dimethyl-6-methylsulfanyl-8-phenyl-3,7-dihydro-purin-2-one 

Relevant articles and documents

Microwave-assisted synthesis of 8-mercapto-3-methyl-7-alkyl xanthines - An improved method

A microwave-assisted synthetic method to prepare novel 8-mercapto-3-methyl- 7-alkyl xanthine compounds is reported. Compared to conventional synthetic route, the new method significantly shortened synthetic steps and reaction time.

Synthesis and structure-activity relationships of 3,7-dimethyl-1- propargylxanthine derivatives, A(2A)-selective adenosine receptor antagonists

A series of 8-substituted derivatives of 3,7-dimethyl-1- propargylxanthine (DMPX) was synthesized and investigated as A(2A) adenosine receptor antagonists. Different synthetic strategies for the preparation of DMPX derivatives and analogues were explored.