55618-81-0

Basic information

• Product Name: 1,5,6,7-Tetrahydro-4-hydroxy-2H-cyclopenta[b]pyridin-2-one
• Synonyms: 1,5,6,7-tetrahydro-4-hydroxy-2h-cyclopenta[b]pyridin-2-one;6,7-dihydro-5H-cyclopenta[b]pyridine-2,4-diol;4-Hydroxy-6,7-dihydro-1H-cyclopenta[b]pyridin-2(5H)-one
• CAS NO: 55618-81-0
• Molecular Formula: C₈H₉NO₂
• Molecular Weight: 151.16
• Mol File: 55618-81-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 390°C
• Flash Point: 190°C
• Appearance: /
• Density: 1.34
• Vapor Pressure: 1.91E-05mmHg at 25°C
• Refractive Index: 1.62
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.50±1.00(Predicted)
• CAS DataBase Reference: 1,5,6,7-Tetrahydro-4-hydroxy-2H-cyclopenta[b]pyridin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5,6,7-Tetrahydro-4-hydroxy-2H-cyclopenta[b]pyridin-2-one(55618-81-0)
• EPA Substance Registry System: 1,5,6,7-Tetrahydro-4-hydroxy-2H-cyclopenta[b]pyridin-2-one(55618-81-0)

Safety Data

• Hazardous Substances Data: 55618-81-0(Hazardous Substances Data)

Usage

General Description

1,5,6,7-Tetrahydro-4-hydroxy-2H-cyclopenta[b]pyridin-2-one is a complex organic compound that falls within the class of chemical compounds known as heterocyclic compounds, specifically, this compound can be categorized under Pyridinones. Its molecular formula can be expressed as C8H9NO2 and it is composed of Oxygen, Nitrogen, Hydrogen, and Carbon atoms. Precise information about the usage or application of this specific chemical compound is limited since it is highly specialized and typically found in scientific research activities or chemical industries. Like other chemical substances, it must always be handled with care, abiding by the safety guidelines to prevent possible hazards.

InChI:InChI=1/C8H9NO2/c10-7-4-8(11)9-6-3-1-2-5(6)7/h4H,1-3H2,(H2,9,10,11)

Upstream product

• 7149-18-0 ethyl 2-amino-1-cyclopentene-1-carboxylate 
• 162397-29-7 methyl 2,5,6,7-tetrahydro-4-hydroxy-2-oxo-1H-pyrindine-3-carboxylate 
• 25115-61-1 N-tert-butylcyclopentanimine 
• 1969-44-4 diphenyl malonate 
• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 
• 55618-82-1 2,4-dihydroxy-6,7-dihydro-5H-[1]pyrindine-3-carboxylic acid ethyl ester 
• 63704-54-1 4-amino-6,7-dihydro-5H-[1]pyrindin-2-ol 

Downstream Products

• 56946-65-7 2,4-dichloro-6,7-dihydro-5H-cyclopenta[b]pyridine 
• 533-37-9 2,3-cyclopentenopyridine 
• 4594-82-5 (+/-)-trans-octahydro[1]pyrindine 

Relevant articles and documents

NOVEL PHARMACEUTICALS

The present invention relates to immune response modifiers of formula (I), which act selectively through agonism, of Toll-Like Receptors (TLRs), uses thereof, processes for the preparation thereof, intermediates used in the preparation thereof and compositions containing said inhibitors. These inhibitors have utility in a variety of therapeutic areas including the treatment of infectious disease such as Hepatitis (e.g. HCV, HBV), genetically related viral infection and cancer.

Retro-Ene Reactions in Heterocyclic Synthesis. II. A Facile Synthetic Method for 4-Hydroxy-2-pyridones

Schiff's bases 1 derived from ketones and t-butylamine reacted with diphenyl malonate, diphenyl methylmalonate and diphenyl phenylmalonate to give 4-hydroxy-2-pyridones 4-6.Schiff's bases 1 on reaction with trimethyl methanetricarboxylate afforded 4-hydro