5564-73-8Relevant articles and documents
N-6-dialkylformamidine-2'-deoxyadenosine phosphoramidites in oligodeoxynucleotide synthesis. Rapid deprotection of oligodeoxynucleotides
Theisen,McCollum,Andrus
, p. 1033 - 1046 (1993)
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Copper-catalyzed coupling reaction of c-ome bonds adjacent to a nitrogen atom with terminal alkynes
Yao, Bangben,Zhang, Yuhong,Li, Yong
supporting information; experimental part, p. 4554 - 4561 (2010/09/10)
(Figure presented) The cross coupling of the C-OMe bond adjacent to a nitrogen atom in dialkoxy-N,N-dialkylmethanamines with terminal alkynes was efficiently approached in the presence of copper catalyst under mild conditions to give 3-amino-1,4-diynes in good yields. The reaction is promoted by phosphine ligands and the chemistry provides a simple and efficient route to 3-amino-1,4-diynes. Importantly, the Michael addition occurred with as-prepared 3-amino-1,4-diynes to give the useful Michael-adducts containing tert-alkylamines in a very convenient way. Further studies revealed that (E)-1,5-diarylpent-1-en-4-yn-3-one was formed through the rearrangement by using the neutral alumina column, and the corresponding imine 2-(1,5-diphenylpent-2- en-4-ynylideneamino)ethanol was obtained in the presence of AgOTf.
A spectroscopic investigation of donor-acceptor-substituted heptalenes
Ott, Philipp,Hansen, Hans-Juergen
, p. 2670 - 2692 (2007/10/03)
It is shown that the heptalene-4,5-dicarboxylates 5 react with their Me group at C(1) with N,N-dimethylformamide dimethyl acetal or other acetals of this type in N,N-dimethylformamide (DMF) to give the corresponding 1-[(E)-2-(N,N-dialkylamino)ethenyl]-sub