55712-26-0

Basic information

• Product Name: 2-(4-methoxyphenyl)-3-phenylquinolin-4(1H)-one
• CAS NO: 55712-26-0
• Molecular Weight: 327.382
• Mol File: 55712-26-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-methoxyphenyl)-3-phenylquinolin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxyphenyl)-3-phenylquinolin-4(1H)-one(55712-26-0)
• EPA Substance Registry System: 2-(4-methoxyphenyl)-3-phenylquinolin-4(1H)-one(55712-26-0)

Safety Data

• Hazardous Substances Data: 55712-26-0(Hazardous Substances Data)

Upstream product

• 1885-29-6 anthranilic acid nitrile 
• 100-44-7 benzyl chloride 
• 835-38-1 1-(2-aminophenyl)-2-phenylethanone 
• 105-13-5 4-Methoxybenzyl alcohol 

Relevant articles and documents

One-Pot Synthesis of 4-Quinolone via Iron-Catalyzed Oxidative Coupling of Alcohol and Methyl Arene

Herein, we describe the iron(III)-catalyzed oxidative coupling of alcohol/methyl arene with 2-amino phenyl ketone to synthesize 4-quinolone. Alcohols and methyl arenes are oxidized to the aldehyde in the presence of an iron catalyst and di-tert-butyl peroxide, followed by a tandem process, condensation with amine/Mannich-type cyclization/oxidation, to complete the 4-quinolone ring. This method tolerates various kinds of functional groups and provides a direct approach to the synthesis of 4-quinolones from less functionalized substrates.