5579-66-8 Usage
Description
Decaethylene glycol, also known as PEG11, is a polymer consisting of 11 ethylene glycol subunits and two terminal hydroxyl groups. It possesses hydrophilic properties due to the PEG linkers, which increase its water solubility under aqueous environments. The hydroxyl groups allow for further derivatization of the compound, making it versatile for various applications.
Uses
Used in Corrosion Inhibition:
Decaethylene glycol is used as a corrosion inhibitor for aluminum surfaces. Its hydrophilic nature and ability to form protective films on metal surfaces contribute to its effectiveness in preventing corrosion.
Used in Pharmaceutical and Chemical Industries:
Decaethylene glycol, due to its hydrophilic properties and the presence of reactive hydroxyl groups, is used as a solubility enhancer and a starting material for the synthesis of various pharmaceutical and chemical compounds. The PEG chains can be further modified to improve the bioavailability and stability of drugs, as well as to create new molecules with specific functions.
Used in Cosmetics and Personal Care Products:
In the cosmetics and personal care industry, Decaethylene glycol is used as a humectant, moisturizer, and viscosity modifier. Its ability to retain water and improve the texture of formulations makes it a valuable ingredient in various products such as creams, lotions, and shampoos.
Used in Biomedical Applications:
Decaethylene glycol can be utilized in the development of hydrogels and other biomaterials for drug delivery systems, tissue engineering, and wound healing applications. The hydrophilic nature and biocompatibility of the PEG chains make them suitable for these applications, where they can help improve the performance and safety of medical devices and treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 5579-66-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,7 and 9 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 5579-66:
(6*5)+(5*5)+(4*7)+(3*9)+(2*6)+(1*6)=128
128 % 10 = 8
So 5579-66-8 is a valid CAS Registry Number.
InChI:InChI=1/C20H42O11/c21-1-3-23-5-7-25-9-11-27-13-15-29-17-19-31-20-18-30-16-14-28-12-10-26-8-6-24-4-2-22/h21-22H,1-20H2
5579-66-8Relevant articles and documents
PROTAC compound for targeted degradation of IDO1, and preparation method and application thereof
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Paragraph 0024-0026; 0036-0037, (2020/06/17)
The invention provides a PROTAC compound represented by formula I and used for targeted degradation of IDO1, and a pharmaceutically acceptable salt, a hydrate or a solvate thereof. In the formula I, Xrepresents -CH2 or -C = O, Y represents -CH2 or -C= O, and n is a natural number from 2 to 9. The PROTAC compound for targeted degradation of the IDO1 has efficient activity of targeted degradation of the IDO1 protein.
A cost-effective, column-free route to ethylene glycol oligomers EG 6, EG10, and EG12
Gothard, Chris M.,Grzybowski, Bartosz A.
experimental part, p. 717 - 722 (2012/04/04)
Although monodisperse ethylene glycol (EG) oligomers are important in a wide range of applications (ranging from drug therapeutics to materials science and engineering), their cost - especially for longer EG oligomers is often prohibitive. For example, decaethylene, EG10, and dodecaethylene, EG12, glycols cost hundreds of dollars per gram, and are only available from most vendors, including Sigma-Aldrich, in the polydispersed form. This high-cost is, in large part, due to laborious nature of synthesis and, above all, purification steps involved. Therefore, the motivation of our work was to design a cost-effective route to the EG oligomers that would altogether avoid the column-chromatography purification. This was achieved by a simple synthetic strategy, which combines bidirectional growth of the EG chains with the protection scheme using easy-to-remove trityl groups. Georg Thieme Verlag Stuttgart · New York.
Synthesis of oligo(ethylene glycol) toward 44-mer
Ahmed, Saleh A.,Tanaka, Mutsuo
, p. 9884 - 9886 (2007/10/03)
A synthetic method for oligo(ethylene glycol) toward 44-mer (FW = 1956.35) is described. Reiteration of Williamson's ether synthesis and hydrogenation to remove protecting benzyl group affords desired oligo(ethylene glycol) toward 44-mer in moderate yields. The advantages in this method are use of commercially easily available materials as starting materials and procedures avoiding difficulty in purification of the products as much as possible.
